DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk6 and ppk14

DIOPT Version :9

Sequence 1:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	552	Identity:	126/552 - (22%)
Similarity:	214/552 - (38%)	Gaps:	143/552 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DGSRKRGKDP-------SLIRTAILATFWEYTERTKVSGMWL-----MRRNRTYGLSRFIWSSVL 70
            |..|::.::|       |.|:.|.......|..|:.:.|::|     |||.     .|.:|:..|
  Fly    15 DRIRRQDQNPLAPVNTKSEIQRAWTLLIDSYISRSHIHGLYLLFLPSMRRR-----MRVLWALAL 74

  Fly    71 LQLLLLSIYLTLLLWLKFYSYPILNTISN-DLSITDVAFPGVTICSPKVVNSERVDRYVKTLKIP 134
            :....:..:::.||..::::......::: ..||..:|||.|.||:...:|..|:........|.
  Fly    75 ICACTVLFHVSYLLGDRYHNKQFQTIVAHAHASIHHIAFPVVIICNKNRLNWSRLPEIKSLYNIT 139

  Fly   135 KEYDMAEVIAGFD-FLNAFTDQSFEPPGHDSYRATDAVL-----RLNNVSIWEAAMAVSPGCFDY 193
            ...|..     || .|.|:...||.     .:.|.|::|     .||:::..|..:.:|..|.:.
  Fly   140 PSQDEL-----FDRILTAYDGFSFH-----KFNAFDSLLGESLDELNHLNFTEIVIQMSWRCDEI 194

  Fly   194 VKRCFWGHTEFQCNQSHEYLSFIPTTAYLGPCCSFNYNPRNASFVPFSANIFGMDGGLTFVGAEG 258
            ::.|.|......|.:     .|.|....||.|.:||...:.                      .|
  Fly   195 LRDCHWQTASRDCCK-----LFRPRRLPLGYCLAFNELEKR----------------------RG 232

  Fly   259 SERNLNTGLIVLV-----HH-----------------------PMDYVTEAAASVTITAQSESFV 295
            :|..:||||::.:     .|                       |::.|..:..:|.:||....|.
  Fly   233 TETGINTGLLLRLLLREGQHAPGNSGLKGFWLTVVESSVWFGFPIEVVPHSRTNVAVTAVYHYFD 297

  Fly   296 EVSPTVQSS----SVEVLELSERKRDCLISGDLQLSNYRQAACLLACQTEAIVKKCGCHPYLLPI 356
            |.:.::.||    .::..|.||..|      .|:...|....|...||...:::.|.|...|...
  Fly   298 ESTLSLPSSWRHCVMDYEEESEHFR------TLEGQKYMLENCQAECQQRYLLRYCNCTVDLFYP 356

  Fly   357 VGNKFKECNLNDTFCYSAN---YDNFK-------------SVRCDQCLPNCYDVTYSTLSYKTDL 405
            ..| :..|.|.|..|.:|:   ..||:             .:.| :||.||     .:|:..||:
  Fly   357 PSN-YPACRLKDLPCLAAHNHLLQNFEQPGEHPYVHREESGLVC-ECLHNC-----KSLTLLTDM 414

  Fly   406 NQHKYSVSRFYSPELLNNDSFV----LRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGLS 466
            .:   ||.:   |.|..|.|.:    |.||..|..:.|.:...:.:|:.|:...|||..||||.|
  Fly   415 RK---SVQQ---PWLQPNSSAIESMWLNVYFKKPSMLVYKTNLIYTWVDLIVSFGGICQLCLGCS 473

  Fly   467 MISVVEFFYYCTYRLYINYQLQKVQQPRKAWQ 498
            :||::||.::..|::           |:..|:
  Fly   474 IISLIEFVFFALYKV-----------PQLYWE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	105/449 (23%)
ppk14	NP_609017.2	ASC	45..483	CDD:279230	117/498 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020