DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk6 and ppk13

DIOPT Version :9

Sequence 1:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	108/503 - (21%)
Similarity:	196/503 - (38%)	Gaps:	100/503 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 EYTERTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLSIYLTLLLWLK-----FYSYPILNTISN 99
            ||.:.:.:.|...:.......:.|..|    :..|:.|.|.:.|| :|     |.:..|...:.:
  Fly     9 EYLKNSTLHGARFIVDKDASWIERIFW----VICLVASWYASWLL-IKASLSAFENNAISFVVES 68

  Fly   100 DLSITDVAFPGVTICSPKVVNSERVDRYVKTL-KIPKEYDMAEVIAGFDFLNAFTDQSFEPPGHD 163
            .....:..||.:.:|..|  |.:|:....:.| ....::.:.||::...|   |..:|:......
  Fly    69 SFRDWNTNFPAIIVCESK--NMDRIQEVAEQLWGADHDFTLEEVLSEIAF---FRGESYHTVHEC 128

  Fly   164 SYRATDAVLRLNNVSIWEAAMAVSPGCFDYVKRCFWGHTEFQCNQSHEYLSFIPTTAYLGPCCSF 228
            |.....|....:|.|.:  |..|...|.|.:..|.|.:..|:|   .:|...:.|.  ||.|.:.
  Fly   129 SGEEVTASCFYSNFSYY--AELVRSSCVDSISNCEWNNKPFEC---CKYFHRMETE--LGICYAI 186

  Fly   229 NYNPRNASFVPFSANIFGMDGGLTFVGAEGSERNLNTGLIVLVHHPMDYVTEAAASV-------T 286
            |........:| ..|::             |.|....|.:.:..|     |||...:       |
  Fly   187 NSMQAGKPKMP-KLNMY-------------SNRGSGPGALKMELH-----TEATVFILGTEEVPT 232

  Fly   287 ITAQSESFVEVSPTVQ----------SSSVEVLELSERKRDCLISGDLQL---SNYRQAACLLAC 338
            :......|:.|.|.:.          .:..|:.:.|..:|:|..:.:..|   ..|..:||.:.|
  Fly   233 LVTPKTDFLVVGPYISFVRYISKRDIENDEEIRQTSVHQRNCRFADENILDVHKFYSYSACTVQC 297

  Fly   339 QTEAIVKKCGCHPYLLPIVGNK--FKECNLNDTFCYSANYDNF-------------KSVRCDQCL 388
            :.:..::.|.|..:|.|   |.  ::.||:....|.:.||::.             |.:.|| ||
  Fly   298 RKDRQMELCNCSSHLSP---NSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGRKGLVCD-CL 358

  Fly   389 PNCYDVTYSTL-SYKTDLNQHKYSVSRFYSPELLNNDSFVLRVYLAKQVVPVIRKVTVMSWIGLL 452
            |:|.:|..:|: ..|.::...:.::||             :.|.|.:......::..|...:.|:
  Fly   359 PSCTEVDITTVYDSKENMAGSQNAISR-------------IEVGLIELPTERYKRNLVRGKLDLV 410

  Fly   453 SDLGGIFNLCLGLSMISVVEFFYYCTYRLYINY-----QLQKVQQPRK 495
            ..:||...|.:|.|::|.||.|||.|.|.|..|     :|:::..|::
  Fly   411 VSIGGTTGLFVGASLLSFVEIFYYITIRPYTTYINEKRRLKRLIIPKR 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	90/432 (21%)
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	99/476 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	5	4.920