Protein Alignment ppk6 and Asic2

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 565
• Identity: 121/565 - (21%)
• Similarity: 191/565 - (33%)
• Gaps: 177/565 - (31%)

  Fly    10 PGKKNS-----KGDGSRKRGKDPSLIRTAILATFWEYTERTKVSG------MWLMRRNRTYGLSR 63
            ||...|     :|.|..:||: |||.||.:.........||...|      :|::....:.|| .
  Rat    38 PGGDRSGDPALQGPGVARRGR-PSLSRTKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSLGL-L 100

  Fly    64 FIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERV---D 125
            ..|||           ..||.||   |:|....:..:.| ..:.||.||:|:...:...|:   |
  Rat   101 LSWSS-----------NRLLYWL---SFPSHTRVHREWS-RQLPFPAVTVCNNNPLRFPRLSKGD 150

  Fly   126 RYVK----TLKIPKEYD---MAEVIAGFD-----FLNAFTDQSFEPPGHDSYRATDAVLRLNNVS 178
            .|..    .|.:|....   ::|::.|.:     |......:.|.||.|
  Rat   151 LYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLFLPPRH---------------- 199

  Fly   179 IWEAAMAVSPGCFDYVKRCFWGHTEFQCNQSHEYLSFIPTTAYLGPCCSFNYNPRNASFV----- 238
                        |:.:...|....      .|:....:.:..|.|..|    .|.|.|.|
  Rat   200 ------------FEGISAAFMDRL------GHQLEDMLLSCKYRGELC----GPHNFSSVFTKYG 242

  Fly   239 ---PFSANIFGMDGGLTFVGAEGSERNLNTGLIVLVHHPMD-YVT----------EAAASVTITA 289
               .|::   |.||.......:|...|   ||.:::....| |:.          ||...|.|.:
  Rat   243 KCYMFNS---GEDGKPLLTTVKGGTGN---GLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHS 301

  Fly   290 QSE-SFVE-----VSPTVQSSSVEVLELSERKRDCLIS--GDLQLSN--------YRQAACLLAC 338
            ||| .|::     |:|..|:    .:...|::...|..  |:.:.|.        |...||.:.|
  Rat   302 QSEPPFIQELGFGVAPGFQT----FVATQEQRLTYLPPPWGECRSSEMGLDFFPVYSITACRIDC 362

  Fly   339 QTEAIVKKCGCH--------PYLLPIVGNKFKEC---------NLNDTFCYSANYDNFKSVRCDQ 386
            :|..||:.|.|.        |:..|   .:.|||         ..:..:|.
  Rat   363 ETRYIVENCNCRMVHMPGDAPFCTP---EQHKECAEPALGLLAEKDSNYCL-------------- 410

  Fly   387 CLPNCYDVTYS------TLSYKTDLNQHKYSVSRF-YSPELLNNDSFVLRVYLAKQVVPVIRKVT 444
            |...|....|:      .:..||..   ||...:| .|.:.::.:..||.::........|.:..
  Rat   411 CRTPCNLTRYNKELSMVKIPSKTSA---KYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKK 472

  Fly   445 VMSWIGLLSDLGGIFNLCLGLSMISVVEFFYYCTYRLYINYQLQK 489
            ......||.|:||...|.:|.|:::::|.|.|.       |:|.|
  Rat   473 AYEVAALLGDIGGQMGLFIGASLLTILELFDYI-------YELIK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	94/464 (20%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	110/538 (20%)