Protein Alignment ppk6 and Asic4

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_036020902.1
• Gene: Asic4 / 241118
• MGIID: 2652846
• Length: 586
• Species: Mus musculus
• Alignment Length: 537
• Identity: 112/537 - (20%)
• Similarity: 194/537 - (36%)
• Gaps: 127/537 - (23%)

  Fly    21 RKRGKDPSLIRTA-------ILATFWEYTERTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLSI 78
            ::.|.:.||:..|       .||||   ...:.:.|:........:||.|.:|:..||..|...:
Mouse    21 KEAGDEQSLLGAAQGPAAPRDLATF---ASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFL 82

  Fly    79 YLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVDRYVKTLKIPKEYDMAEVI 143
            |....|...:.:.|.|..:..........||.||:|:        ::|:           ....:
Mouse    83 YQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCN--------INRF-----------RHSAL 128

  Fly   144 AGFDFLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAAMAVSPGCFDYVKRC-FWGHTEFQCN 207
            :..|..:........|...|.:||  |.||.....:.:..........|.:|.| |.||   .|:
Mouse   129 SDADIFHLANLTGLPPKDRDGHRA--AGLRYPEPDMVDILNRTGHQLADMLKSCNFSGH---HCS 188

  Fly   208 QSHEYLSFIPTTAYLGPCCSFNYNPRNASFVPFSANIFGMDGGLTF-----------VGAEGSER 261
            .|:..:.:   |.| |.|.:||.:|:  |.:|..|.  ||..||..           :..|.:|.
Mouse   189 ASNFSVVY---TRY-GKCYTFNADPQ--SSLPSRAG--GMGSGLEIMLDIQQEEYLPIWRETNET 245

  Fly   262 NLNTGLIVLVHHPMD--YVTEAAASVTITAQSESFVEVSPTVQSSSVEVLELSERKRDCLISGDL 324
            :...|:.|.:|...:  |:.:....|:...|:        .|......:..|.:...:|....:|
Mouse   246 SFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQT--------FVSCQEQRLTYLPQPWGNCRAESEL 302

  Fly   325 Q------LSNYRQAACLLACQTEAIVKKCGCH------PYLLPIVG--------NKFKECNLNDT 369
            :      .|.|..:||.|.|:.||::::|.|.      .:|.|:.|        ::.:.|  ..|
Mouse   303 REPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGGHLQPVFGATLLSSRTSRRQRC--MRT 365

  Fly   370 FCYSANYDNFKSVRCDQ----------CLPN----CYDVTYSTLS--------YKTDLNQHKY-- 410
            .| :..|.:.:.:.|..          |.||    |.|.|..:|.        ..|..|..:|
Mouse   366 TC-TRIYTHERVLMCMSGYLHMGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGK 429

  Fly   411 ----------SVSRFYSPELLNNDSF------VLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIF 459
                      ..:|:.:.:...|:::      ||.|:........:.:........||.||||..
Mouse   430 EISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQM 494

  Fly   460 NLCLGLSMISVVEFFYY 476
            .|.:|.|:::::|...|
Mouse   495 GLFIGASILTLLEILDY 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	93/464 (20%)
Asic4	XP_036020902.1	ENaC	40..535	CDD:273304	108/518 (21%)