Protein Alignment ppk6 and Asic3

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 504
• Identity: 100/504 - (19%)
• Similarity: 168/504 - (33%)
• Gaps: 138/504 - (27%)

  Fly    61 LSRFIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVD 125
            |.|.:|::.:|..|...:| .:...:::|......|..::.....:.||.||:|:   :|..|..
Mouse    41 LRRGLWATAVLLSLAAFLY-QVAERVRYYGEFHHKTTLDERESHQLTFPAVTLCN---INPLRRS 101

  Fly   126 RYVKTLKIPKEYDMA-EVIAGFD------FLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAA 183
            |..     |.:...| ..:.|.|      :|.|. .|...|||
Mouse   102 RLT-----PNDLHWAGTALLGLDPAEHAAYLRAL-GQPPAPPG---------------------- 138

  Fly   184 MAVSPGCFD----YVKRCFWGHT----EFQCNQSHEYL---SFIPTTAYLGPCCSFNYNPRNASF 237
            ...|| .||    |.:.   ||:    ...|....:..   :|......:|.|.:||...:.|..
Mouse   139 FMPSP-TFDMAQLYARA---GHSLEDMLLDCRYRGQPCGPENFTVIFTRMGQCYTFNSGAQGAEL 199

  Fly   238 VPFSANIFGMDGGLTF-----------VGAEGSERNLNTGLIVLVH---HP--MDYVTEAAA--- 283
            :.....  |...||..           :..:..|.....|:.|.:|   .|  :|.:...||
Mouse   200 LTTPKG--GAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGH 262

  Fly   284 SVTITAQSESFVEVSP---TVQSSSVEVLELSERKRDCLISGDLQLSNYRQAACLLACQTEAIVK 345
            ...::.|.:....:.|   ...::||:. :......|.|.|.. ....|....|.|||::..:.:
Mouse   263 QTFVSCQQQQLSFLPPPWGDCNTASVDP-DFDPEPSDPLGSPS-SSPPYSLIGCRLACESRYVAR 325

  Fly   346 KCGCHPYLLPIVGN-------KFKEC------------------------NLNDTFCYSANYDNF 379
            ||||....:|  ||       ::|:|                        .|.....:.|.....
Mouse   326 KCGCRMMHMP--GNSPVCSPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQVLLFLALRPAD 388

  Fly   380 KSVRCDQCL-PN-CYDVTYSTLSYKTDLNQ-------------HKYSVSRFYSPELLNNDSFVLR 429
            ..:|.|.|: || |     :|..|..:|:.             .||:.|..|    :..:..||.
Mouse   389 AMLRKDTCVCPNPC-----ATTRYAKELSMVRIPSRASARYLARKYNRSETY----ITENVLVLD 444

  Fly   430 VYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGLSMISVVEFF-YYC 477
            ::........:.:........||.|:||...|.:|.|:::::|.. |.|
Mouse   445 IFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLC 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	92/477 (19%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	100/504 (20%)