Protein Alignment ppk6 and asic1

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_004912018.1
• Gene: asic1 / 100489966
• XenbaseID: XB-GENE-977699
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 477
• Identity: 110/477 - (23%)
• Similarity: 178/477 - (37%)
• Gaps: 100/477 - (20%)

  Fly    59 YGLSRFIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSER 123
            :...|.||....|..|.|.:|:.....:.::.||.:..: :::|...:.||.||.|:   :|..|
 Frog    38 FSCRRLIWVLCFLGSLSLLLYVCTERIIYYFEYPHVTKL-DEISTPRMIFPAVTFCN---LNEFR 98

  Fly   124 VDRYVKTLKIPKEYDMAEVIAGFDFLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAA--MAV 186
            ..|..|.    ..|...|:::   .||    ..:|.|  ||..|.:.|:.:    :.:.|  ...
 Frog    99 FSRVTKN----DLYHAGELLS---LLN----NRYELP--DSQLADEKVMEI----LQDKANFRNF 146

  Fly   187 SPGCFDYVKRCFWGHTE-------FQCNQSHEYLS---FIPTTAYLGPCCSFNYNPRNASFVPFS 241
            .|..|:  .|.|:..|.       ..|....|..|   |:|.....|.|.:||
 Frog   147 KPKPFN--MREFYDRTGHDIREMLLSCKYRGEECSVDDFVPVFTRYGKCYTFN------------ 197

  Fly   242 ANIFGMDGGLTFVGAEGSERNLNTGLIVLVHHPMD-YVT----------EAAASVTITAQSE-SF 294
               .|.:|....|..:|...|   ||.:::....| |:.          ||...|.|.:|.| .|
 Frog   198 ---SGRNGRSPLVTTKGGTGN---GLELMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPF 256

  Fly   295 VE-----VSPTVQSSSVEVLELSERK--------RDCLISG-DLQ-LSNYRQAACLLACQTEAIV 344
            ::     |:|..|:    .:...|::        .||..|. |.: ...|..:||.:.|:|..:|
 Frog   257 IDQLGFGVAPGFQT----FVSCQEQRLTYLPPPWGDCKSSAMDSEFFDTYSISACRIDCETRYLV 317

  Fly   345 KKCGCHPYLLP-----IVGNKFKECNLNDTFCYSANYDNFKSVRCDQCLPNCYDVTYSTLSYKTD 404
            :.|.|....:|     .....:||| .:....:....||...|....|....|....|.:...:.
 Frog   318 ENCNCRMVHMPGDAAYCTPELYKEC-ADPALDFLVEKDNDFCVCETPCNMTRYGKELSMVKIPSK 381

  Fly   405 LNQH----KYSVSRFYSPELLNNDSFVLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGL 465
            .:..    ||:.|..|..|    :..||.::........|.:.......|||.|:||...|.:|.
 Frog   382 ASARYLAKKYNKSEQYIAE----NILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGA 442

  Fly   466 SMISVVEFFYYCTYRLYINYQL 487
            |:::|:|.|.| .|.: :.|:|
 Frog   443 SILTVLELFDY-AYEV-LRYKL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	99/438 (23%)
asic1	XP_004912018.1	ENaC	18..507	CDD:273304	110/477 (23%)