Protein Alignment Hacl and ilvB

DIOPT Version :10

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_418127.1
• Gene: ilvB / 948182
• ECOCYCID: EG10494
• Length: 562
• Species: Escherichia coli
• Alignment Length: 572
• Identity: 162/572 - (28%)
• Similarity: 254/572 - (44%)
• Gaps: 101/572 - (17%)

  Fly     8 QIIAESLKQQGVEYVFGIIG---IPVIE-LSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTGKPG 68
            :.|...|:|||::.|.||.|   :||.: ||   |:..:::|..|:||.|.:.||.:....|||.
E. coli    17 EFIVHFLEQQGIKIVTGIPGGSILPVYDALS---QSTQIRHILARHEQGAGFIAQGMARTDGKPA 78

  Fly    69 VCLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYCK--YAARP 131
            ||:..||||..::...:|:|:::..|||.|.|.......|...|||.....:|.|..|  |..|
E. coli    79 VCMACSGPGATNLVTAIADARLDSIPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVR- 142

  Fly   132 ATAALIPLHVEK-------AVRYATYGRPGVAYLDFPGNILQSKAQEASIYKALAHPAPPLAYPP 189
                    |:|:       |.|.|..||||..::|.|.:: |:...|.....|:|..|...|:
E. coli   143 --------HIEELPQVMSDAFRIAQSGRPGPVWIDIPKDV-QTAVFEIETQPAMAEKAAAPAF-- 196

  Fly   190 HDDVIR-AAKLLRQAKRPLVIVGKGSAYAHAENTLRHFIENTNLPFLPTPMGKGVVSDTAPQCVS 253
            .::.|| ||.::..||||::.:|.|...|.|.  :|...|...||...|.|..|::....|..:.
E. coli   197 SEESIRDAAAMINAAKRPVLYLGGGVINAPAR--VRELAEKAQLPTTMTLMALGMLPKAHPLSLG 259

  Fly   254 -------SARTLALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPEELHNSVVASVAI 311
                   .:....||:||::::||||.: ....||..::..:.|.|.|||:..||.......|||
E. coli   260 MLGMHGVRSTNYILQEADLLIVLGARFD-DRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAI 323

  Fly   312 QADIRPFAEQLFEQMNAVNFRFGYEQDWWKQLAVKCKQNRDTVQKMSLNTETPLNYYAVFHHLRE 376
            |||:.....||...:.|      ..:..|.||....::........:.:   ||::|.:.:.:..
E. coli   324 QADVDDVLAQLIPLVEA------QPRAEWHQLVADLQREFPCPIPKACD---PLSHYGLINAVAA 379

  Fly   377 LLPKDTIIVSEGANTMDIGRSMLLNEQ------PRHRLDAGTFGTMGVGPGFAVAAALFCRDFAP 435
            .:..:.||      |.|:|:..:...|      ||..|.:|..||||.|...|:.|||    ..|
E. coli   380 CVDDNAII------TTDVGQHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAAL----ANP 434

  Fly   436 GKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVIVNN---------------NGIY--------- 476
            .::|||..||.:...:..|:.|....:|.|.|:::||               .|::
E. coli   435 DRKVLCFSGDGSLMMNIQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKIN 499

  Fly   477 -----GGFDKDTFEAIRSEGD----LTQI--TPPSALGVQVRYEEMMKMFGM 517
                 .||..:|.: :.:|.|    |.:|  .|..|| :.||.:...|::.|
E. coli   500 FMQIAAGFGLETCD-LNNEADPQASLQEIINRPGPAL-IHVRIDAEEKVYPM 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	162/572 (28%)
ilvB	NP_418127.1	PRK08155	1..562	CDD:181257	162/572 (28%)