Protein Alignment Hacl and oxc

DIOPT Version :10

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_416874.1
• Gene: oxc / 946845
• ECOCYCID: G7236
• Length: 564
• Species: Escherichia coli
• Alignment Length: 563
• Identity: 227/563 - (40%)
• Similarity: 343/563 - (60%)
• Gaps: 39/563 - (6%)

  Fly     5 EAVQIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTGKPGV 69
            :.:.||.|:|||..::.::|::||||.:::...||.|::|||.|:||:|.|||.|.|:||.|||:
E. coli     9 DGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIGFRHEQSAGYAAAASGFLTQKPGI 73

  Fly    70 CLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGI--GGFQECPQVELSRPYCKYAARPA 132
            ||.||.||.|:....:|||.||.:|:|:|.|::::....:  |.::|..|:..::||.|.|.|..
E. coli    74 CLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVN 138

  Fly   133 TAALIPLHVEKAVRYATYGRPGVAYLDFPGNILQSKAQE----ASIYKALAHPAPPLAYPPHDDV 193
            ....:.:.:.:|:|.:..||||..|||.|.|:|.:..::    .:|.| :.:|:|.| .|....|
E. coli   139 QPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVK-VENPSPAL-LPCPKSV 201

  Fly   194 IRAAKLLRQAKRPLVIVGKGSAYAHAENTLRHFIENTNLPFLPTPMGKGVVSDTAPQCVSSARTL 258
            ..|..||.:|:|||:|:|||:||:.|:..||.|||:..:||||..|.||::.||.|...::||:.
E. coli   202 TSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSF 266

  Fly   259 ALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPEELHNSVVASVAIQADIRPFAEQLF 323
            ||..||||:|:||||||:|..|| ..:..|.:|||:||.|:|:.::...:|.:..||....:.:.
E. coli   267 ALANADVVMLVGARLNWLLAHGK-KGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGML 330

  Fly   324 EQMNAVNFRFGYEQDWWKQLAVKCKQNRDTVQKM--SLNTET-PLNYYAVFHHLRELL--PKDTI 383
            .::....|.....  |...|.:..:||   .|||  .|:|:| ||||:.....:|::|  .:|..
E. coli   331 AELKQNTFTTPLV--WRDILNIHKQQN---AQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIY 390

  Fly   384 IVSEGANTMDIGRSMLLNEQPRHRLDAGTFGTMGVGPGFAVAAALFCRDFAPGKRVLCVEGDSAF 448
            :|:|||||:|..|:::...:||.|||.||:|.||:|.|:|:.|::     ..|..|:.:||||||
E. coli   391 LVNEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASV-----TSGSPVVAIEGDSAF 450

  Fly   449 GFSGMEIETMVRYKLPVTIVIVNNNGIYGGFDKDTFEAIRSEG-DLTQITPPSALGV--QVRYEE 510
            |||||||||:.||.|||||||.||.|||           |.:| ||:....||...:  ..||::
E. coli   451 GFSGMEIETICRYNLPVTIVIFNNGGIY-----------RGDGVDLSGAGAPSPTDLLHHARYDK 504

  Fly   511 MMKMFGMKGYFCTEIEQLQAAVKAANQLTDRPTIINVAISPSS 553
            :|..|...||..|..::|:.|:....| :.:||||||.|.|::
E. coli   505 LMDAFRGVGYNVTTTDELRHALTTGIQ-SRKPTIINVVIDPAA 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	226/557 (41%)
oxc	NP_416874.1	oxalate_oxc	6..559	CDD:132298	227/563 (40%)