Protein Alignment Hacl and PDC5

DIOPT Version :9

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_013235.1
• Gene: PDC5 / 850825
• SGDID: S000004124
• Length: 563
• Species: Saccharomyces cerevisiae
• Alignment Length: 553
• Identity: 120/553 - (21%)
• Similarity: 227/553 - (41%)
• Gaps: 79/553 - (14%)

  Fly     1 MAEVEAVQIIAESLKQQGVEYVFGIIG-IPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLT 64
            |:|:...:.:.|.|.|.....|||:.| ..:..|...::..|:::.|..||..|.|||.  ||..
Yeast     1 MSEITLGKYLFERLSQVNCNTVFGLPGDFNLSLLDKLYEVKGMRWAGNANELNAAYAAD--GYAR 63

  Fly    65 GKPGVCLVVS-GPGLLHVTGGMANA---QVNCWPLIVIGGATNQD-----HEGIGGFQECPQVEL 120
            .|...|::.: |.|.|....|:|.:   .|....::.:...::|.     |..:|.........:
Yeast    64 IKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRM 128

  Fly   121 SRPYCKYAARPATAALIPLHVEKAVRYATYGRPGVAYLDFPGNILQSKAQEASIYKALAHPAPPL 185
            |....:..|.....|..|..:::.:| .||......||..|.|::     :.::...|......|
Yeast   129 SANISETTAMITDIANAPAEIDRCIR-TTYTTQRPVYLGLPANLV-----DLNVPAKLLETPIDL 187

  Fly   186 AYPPHD-----DVIR-AAKLLRQAKRPLVIVGKGSAYAHAENTLRHFIENTNLPFLPTPMGKGVV 244
            :..|:|     :|:| ..:|::.||.|:::....::....:...:..::.|..|...||||||.:
Yeast   188 SLKPNDAEAEAEVVRTVVELIKDAKNPVILADACASRHDVKAETKKLMDLTQFPVYVTPMGKGAI 252

  Fly   245 SDTAPQ-------CVSSART-LALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPEEL 301
            .:..|:       .:|.... .|::.||::|.:||.|: ..:.|......|....::...:..::
Yeast   253 DEQHPRYGGVYVGTLSRPEVKKAVESADLILSIGALLS-DFNTGSFSYSYKTKNIVEFHSDHIKI 316

  Fly   302 HNSVVASVAIQADIRPFAEQLFEQMNAVNFRFGYEQDWWKQLAVKCKQNRDTVQKMSLNTETPLN 366
            .|:....|.::..::...:.:.|.:..           :|.:||..   |..:.| |....||:.
Yeast   317 RNATFPGVQMKFALQKLLDAIPEVVKD-----------YKPVAVPA---RVPITK-STPANTPMK 366

  Fly   367 YYAVFHHLRELLPKDTIIVSE-GANTMDIGRSMLLNEQPRHRLDAGTFGTMGVGPGFAVAAALFC 430
            ...:::||...|.:..|:::| |.:...|.::....:.  :.:....:|::|...|..:.|.:..
Yeast   367 QEWMWNHLGNFLREGDIVIAETGTSAFGINQTTFPTDV--YAIVQVLWGSIGFTVGALLGATMAA 429

  Fly   431 RDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVIVNNNGIYGGFDKDTFEAIRSEGDLTQ 495
            .:..|.|||:...||.:...:..||.||:|:.|...|.::||||.       |.|.:
Yeast   430 EELDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYIFVLNNNGY-------TIEKL-------- 479

  Fly   496 ITPPSALGVQVRYEE--------MMKMFGMKGY 520
            |..|.|     .|.|        ::..||.:.|
Yeast   480 IHGPHA-----EYNEIQGWDHLALLPTFGARNY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	118/546 (22%)
		TPP_PYR_POX_like	8..161	CDD:132918	38/162 (23%)
		TPP_enzyme_M	195..322	CDD:278628	26/135 (19%)
		TPP_BZL_OCoD_HPCL	367..550	CDD:238962	38/163 (23%)
PDC5	NP_013235.1	PDC1	1..563	CDD:226470	120/553 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S956
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860