Protein Alignment Hacl and hac1

DIOPT Version :10

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_595484.1
• Gene: hac1 / 2541142
• PomBaseID: SPBC725.04
• Length: 568
• Species: Schizosaccharomyces pombe
• Alignment Length: 569
• Identity: 231/569 - (40%)
• Similarity: 348/569 - (61%)
• Gaps: 19/569 - (3%)

  Fly     8 QIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTGKPGVCLV 72
            :::|::|....|:.||||:||||||:..|.||:|::::|.||||:|.|||.|.||||.:||||:|
pombe     7 ELVAKTLLDLEVKVVFGIVGIPVIEICEAIQASGIRFVGFRNEQSAAYAATAYGYLTQRPGVCVV 71

  Fly    73 VSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYCKYAARPATAALI 137
            |.|||::|...|:.|::.|.|||:::.|::....:..|.|||..||....|:.|.|.||.:..::
pombe    72 VGGPGVVHAMAGVFNSKTNRWPLLLLAGSSETFQQNCGAFQELDQVSYLSPHTKLAVRPPSPKMV 136

  Fly   138 PLHVEKAVRYATYGRPGVAYLDFPGNILQSKAQEASIYKALAHPAPPLAYPPHDDVIRAAKLLRQ 202
            ...:.:|.|.:..|.||..|:|.|.|.::|...:.........|:.|...|....:.:||..|:.
pombe   137 VDSIRRAYRVSMTGTPGTCYVDLPANYIESTVDDFPKDPLPPIPSSPKCAPDPTQLQKAAYYLKN 201

  Fly   203 AKRPLVIVGKGSAYAHAENTLRHFIENTNLPFLPTPMGKGVVSDTAPQCVSSARTLALQKADVVL 267
            ||.||::||||:|||.||..|..|:|:|.:||||:|||||::.::.|..|||||:.||:.|||||
pombe   202 AKAPLLVVGKGAAYACAEKQLLEFVEHTGIPFLPSPMGKGLLPESHPLNVSSARSAALRNADVVL 266

  Fly   268 LLGARLNWILHFGKAPRYDKDVKFIQVDINPEEL-HNSVVASVAIQADIRPFAEQLFEQMNAVNF 331
            |.|||||||..:|..|::..:.||||:|.|.|.| :|:....:||.||:....:.||:.:....:
pombe   267 LAGARLNWIFQYGLPPKWSPNAKFIQIDTNAETLGNNAADLDLAIWADVGLTIDCLFKLVQTWKY 331

  Fly   332 RFGYEQDWWKQL-AVKCKQNRDTVQKMSLNTETPLNY--YAVFHHLRELLPK---DTIIVSEGAN 390
            ..|....:.:.| ..:.|..:..::....:....:||  |.|...|:.|..|   :...||||||
pombe   332 SVGISTPYLRTLNETRSKNEKKALESRKSSIPLQMNYALYVVNEELQSLSLKSKRNITWVSEGAN 396

  Fly   391 TMDIGRSMLLNEQPRHRLDAGTFGTMGVGPGFAVAAALFCRDFA-PGKRVLCVEGDSAFGFSGME 454
            |||.||.:|....||.||||||..|||||.|:|:|:|     || ...:::.||||||||||.||
pombe   397 TMDRGRQLLEVTHPRGRLDAGTMSTMGVGMGYAIASA-----FAHSSDKIVVVEGDSAFGFSAME 456

  Fly   455 IETMVRYKLPVTIVIVNNNGIYGGFDKDTFEAIRSEGDLTQITPPSALGVQVRYEEMMKMFGMKG 519
            :||.:|.:|.:.::::||||:|.|.|.|.:|.:|....|    |.:|||..:||:::.:..|.||
pombe   457 LETAIRNQLDLLVIVINNNGVYHGLDTDAYETLRDNHQL----PTTALGTSIRYDQICEACGGKG 517

  Fly   520 YFCTEIEQLQAAVKAANQLTDRPTIINVAISPSSDRKPQSFNWLTESKL 568
            :|....|.|:::::.|.| |...::|||.:.|.:.|| .:|.|::.:|:
pombe   518 FFVKNEEDLRSSLRKAWQ-TSSVSLINVMVDPEAARK-LTFAWMSSTKV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	225/551 (41%)
hac1	NP_595484.1	PRK09259	8..550	CDD:236433	226/551 (41%)