Protein Alignment Hacl and Ilvbl

DIOPT Version :9

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_030100875.1
• Gene: Ilvbl / 216136
• MGIID: 1351911
• Length: 644
• Species: Mus musculus
• Alignment Length: 613
• Identity: 169/613 - (27%)
• Similarity: 278/613 - (45%)
• Gaps: 87/613 - (14%)

  Fly     1 MAEVEAVQI------IAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQA 59
            |.:|:...|      :|..|:..||.:||.::|..:..|.:|.:..|::.:..|:|..|.:||.|
Mouse    55 MHKVDKTSIRHGGESVAAVLRAHGVRFVFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADA 119

  Fly    60 IGYLTGKPGVCLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPY 124
            :..|||..||..|.:||||.:....:.||||...|::::|||.:...:..|..|...|:.|.||.
Mouse   120 VARLTGTVGVAAVTAGPGLTNTVTAVKNAQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPL 184

  Fly   125 CKYAARPATAALIPLHVEKAVRYATYGRPGVAYLDFP------------------------GNIL 165
            ||:.|.......|...:..|:..|..|.||..:::.|                        |.::
Mouse   185 CKFCASVRRVRDIVPTLRTAIAAAQSGTPGPVFVELPLDVLYPYFMVEKEMIPTKLPNSLMGRVV 249

  Fly   166 QSKAQE--ASIYKALAHPAP----PLAYP--PHDDVIRAAKLLRQAKRPLVIVGKGSAYAHA-EN 221
            ....|.  |:::.....|.|    ||..|  ....|.|..::|.:|||||:::|..:..... .|
Mouse   250 VWYLQNCLANLFVGAWEPRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPAN 314

  Fly   222 TLRHFIENTNLPFLPTPMGKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGKAPRYD 286
            .||..:|...:|.....|.:|::....|..:...|:.||:|||||:|.||..::.|.:|:.  .:
Mouse   315 KLRAAVETLGVPCFLGGMSRGLLGRNHPLHIRQNRSAALKKADVVVLAGAVCDFRLSYGRV--LN 377

  Fly   287 KDVKFIQVDINPEE-LHNSVV---ASVAIQADIRPFAEQLFE----QMNAVNFRFGYEQDWWKQL 343
            :....|.|:.|.:: |.||.:   ...|:|.|:..|..:|.|    ||        :..||.::|
Mouse   378 RKSSIIIVNRNRDDLLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQM--------WSSDWAEEL 434

  Fly   344 AVKCKQNRDTVQKMSLNTETP----LNYYAVFHHLRELLPKDTIIVSEGANTMDIGRSMLLNEQP 404
            ....:|...|.:..:|   .|    ||...|...:.|.||.:.::|.:|.:.:.....::....|
Mouse   435 RKADQQKEQTYRDKAL---MPVLQHLNPVWVLQQVEETLPDNALLVVDGGDFVATAAYLVQPRGP 496

  Fly   405 RHRLDAGTFGTMGVGPGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVI 469
            ...||.|.|||:|||.|||:.|.| |:   |...|.|:.||.|||:|.:|.:|.||:|:|| |.:
Mouse   497 LRWLDPGAFGTLGVGAGFALGAKL-CQ---PEAEVWCLFGDGAFGYSLIEFDTFVRHKVPV-IAL 556

  Fly   470 VNNNGIYGGFDKDTFEAIRSEGDLTQITPPSALGVQVRYEEMMKM---FGMKGYFCT--EIEQLQ 529
            |.|:   .|:.:.:.|.:...|        |.:...:.|.:..|.   .|.:|...:  ..:|:.
Mouse   557 VGND---AGWTQISREQVPRLG--------SDVACSLAYTDYHKAAMGLGAQGLILSRDNKDQVV 610

  Fly   530 AAVKAANQLTD--RPTIINVAISPSSDR 555
            ..::...||..  ...::|:.|..:..|
Mouse   611 KVLREGQQLCQDGHAVVVNILIGRTDFR 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	166/601 (28%)
		TPP_PYR_POX_like	8..161	CDD:132918	50/158 (32%)
		TPP_enzyme_M	195..322	CDD:278628	39/131 (30%)
		TPP_BZL_OCoD_HPCL	367..550	CDD:238962	53/189 (28%)
Ilvbl	XP_030100875.1	PRK05858	65..598	CDD:235629	159/561 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62113
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100369
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720