Protein Alignment Hacl and T26C12.1

DIOPT Version :9

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_500306.1
• Gene: T26C12.1 / 177095
• WormBaseID: WBGene00020831
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 158/603 - (26%)
• Similarity: 265/603 - (43%)
• Gaps: 81/603 - (13%)

  Fly     8 QIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTGKPGVCLV 72
            :::|..||...||.:|.:.|..:..:.:|.:..|:|.:..|:|..|.:||.|:..|....||..|
 Worm    60 ELVASVLKAHDVEEIFVLCGGHISPILVAAEKLGIKIVDTRHEVTAVFAADAVARLRQSIGVAAV 124

  Fly    73 VSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYCKYAARPATAALI 137
            .:||||.:....:.|||:...||::||||.....:|.|..|:..|:.|.||.|||.||......|
 Worm   125 TAGPGLTNTITAVKNAQMAESPLLLIGGAAPTLLKGRGALQDIDQMVLFRPLCKYVARVERLRDI 189

  Fly   138 PLHVEKAVRYATYGRPGVAYLDFPGNIL----------------QSKAQEASIYKALAH------ 180
            ...|.:|::.|..|.||..:::||.::|                :...|.|..:....|
 Worm   190 VPTVREAIKAAKSGCPGPVFVEFPVDVLYPYELVVKEIGFNPNAKGFIQRALNFYLRCHVSRQFG 254

  Fly   181 ---------PAPP-LAYPPHDDVIRAAKLLRQAKRPLVIVGKGSAYAHAENT-LRHFIENTNLPF 234
                     |.|. :..|..:.:....:|::.||||::::|..:.....:.. |...:|....|.
 Worm   255 NAWAPQTITPLPTNIPMPKSEKIQEIVQLVKSAKRPVLLIGSQATLPPVKPADLVKAVEALGCPV 319

  Fly   235 LPTPMGKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPE 299
            ....|.:|::....|..:...|..||:.||:.:|.|...::.|.:|:.  ..|..|.:.::.|..
 Worm   320 FLGGMARGLLGKDHPLQMRQVRRDALKDADLTILAGTVCDFRLSYGRT--LSKKSKIVALNRNSS 382

  Fly   300 ELHNSVVA----SVAIQADIRPFAEQLFEQMNAVNFRF-GYEQDWWKQLAVKCKQN-----RDTV 354
            :|..:..|    .|::|||:   |..|.:..||:.... ....:|.|.|..|..:.     :...
 Worm   383 QLTKNEKAFWNSDVSVQADV---ATSLVQVANALGANHTTTPTEWVKSLREKDDEKESANAKKME 444

  Fly   355 QKMSLNTETPLNYYAVFHHLRELLPKDTIIVSEGANTMDIGRSMLLNEQPRHRLDAGTFGTMGVG 419
            ||::.....|||:   ...|.:.||.|.|:|::|.:.:.....::....|...||.|.|||:|||
 Worm   445 QKLTNGFLNPLNF---LRTLDQSLPDDAILVADGGDFVGSAAYIVRPRGPLQWLDPGAFGTLGVG 506

  Fly   420 PGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVIVNNNGIYGGFDKDTF 484
            .|||:.|    :...|.:.|..:.||.:.|:|.||.:|..|:|||| |.||.|:..:....::..
 Worm   507 GGFALGA----KTVYPKRPVYIIWGDGSCGYSLMEYDTFARHKLPV-IGIVGNDACWTQIAREQV 566

  Fly   485 EAIRSE--GDLTQITPPSALGVQVRYEEMMKMFGMKGYFCTE---------IEQLQAAVKAANQL 538
            ...:|.  .||          .:.||:.:.|..|..|....|         :::..|..::..|
 Worm   567 PMFQSSVAVDL----------ARTRYDNVAKSLGSWGETIDESNADSARKILDEALAVCRSGEQ- 620

  Fly   539 TDRPTIINVAISPSSDRK 556
               ..::||.|..:..|:
 Worm   621 ---SALVNVLIGKTDFRE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	157/597 (26%)
		TPP_PYR_POX_like	8..161	CDD:132918	52/152 (34%)
		TPP_enzyme_M	195..322	CDD:278628	31/131 (24%)
		TPP_BZL_OCoD_HPCL	367..550	CDD:238962	52/193 (27%)
T26C12.1	NP_500306.1	PRK05858	52..632	CDD:235629	157/598 (26%)
		TPP_PYR_POX_like	60..214	CDD:132918	53/153 (35%)
		TPP_enzyme_M	277..408	CDD:278628	32/135 (24%)
		TPP_BZL_OCoD_HPCL	454..628	CDD:238962	55/195 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62113
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100369
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720