Protein Alignment Hacl and ilvbl

DIOPT Version :9

• Sequence 1: NP_611460.1
• Gene: Hacl / 37285
• FlyBaseID: FBgn0034488
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001120212.1
• Gene: ilvbl / 100145261
• XenbaseID: XB-GENE-967603
• Length: 626
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 171/600 - (28%)
• Similarity: 281/600 - (46%)
• Gaps: 81/600 - (13%)

  Fly     8 QIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTGKPGVCLV 72
            :::|:.|:..||.:||.:.|..:..:.:|.:..|::.:..|:|..|.:||.|:..|:|..||..|
 Frog    50 EVVAKVLQAHGVRFVFTLPGGHISPIVVACEKLGIRIVDTRHEATAVFAADAVARLSGTVGVAAV 114

  Fly    73 VSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYCKYAARPATAALI 137
            .:||||.:....:.|||:...||::||||:....:|.|..|:..|:.|.:|.||..:...|...|
 Frog   115 TAGPGLTNTVTAIKNAQMAESPLLLIGGASATLLQGRGALQDIDQMSLFKPICKSCSSVRTIREI 179

  Fly   138 PLHVEKAVRYATYGRPGVAYLDFPGNIL-----------QSKAQEASIYKAL------------- 178
            ...:.||:..|..|.||..:::||.:||           ...|.:..:.||:
 Frog   180 VPVLRKAMAEAQSGTPGPVFVEFPIDILYPYHIVHKELSPKGAPKGIVGKAITWYLQNHLNNLFA 244

  Fly   179 -------AHPAP---PLAYPPHDDVIRAAKLLRQAKRPLVIVGKGSAYAHAE-NTLRHFIENTNL 232
                   ..|.|   |.|.|.  .:.:..:|:.:||:|:.::|......... .|||..:|:..:
 Frog   245 GAWEPRDVSPLPLSIPQASPM--QIQQCIELVSRAKKPVFLLGSQVTLPPMPVETLRKSLESLGI 307

  Fly   233 PFLPTPMGKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDIN 297
            |.....|.:|::...:|..:...|..||::||:|:|.|...::.|.:|:.  ..:..|.|.|:.:
 Frog   308 PCFLGGMARGMLGRDSPLHIRQNRREALKEADLVILAGTVCDFRLSYGRV--LSRRSKIIAVNRD 370

  Fly   298 PEE-LHNSVV---ASVAIQADIRPFAEQLFEQMNAVNFRFGY--EQDWWKQL----AVKCKQNRD 352
            ..: |.||.:   .|||||.|...|..:|.|.:|      ||  ..:|.:.|    ..|.|.||
 Frog   371 RSQLLKNSDMFWKPSVAIQGDAGSFIVKLCEGLN------GYTCPTEWTEGLKTGYVTKEKTNR- 428

  Fly   353 TVQKMSLNTETPLNYYAVFHHLRELLPKDTIIVSEGANTMDIGRSMLLNEQPRHRLDAGTFGTMG 417
              ||....||..||...|.|.:.:.:.:|:|||::|.:.:.....:|....|...||.|.|||:|
 Frog   429 --QKAEEKTERHLNPLKVLHLVDDAMAEDSIIVADGGDFVGSAAYILRPRGPLCWLDPGAFGTLG 491

  Fly   418 VGPGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVIVNNNGIYGGFDKD 482
            ||.|||:.|.| ||   |...|..|.||.:.|:|.:|.:|..|:|.|| |.:|.|:..:....::
 Frog   492 VGGGFALGAKL-CR---PDSEVWIVFGDGSLGYSIVEFDTYTRHKTPV-IALVGNDACWNQISRE 551

  Fly   483 TFEAIRSEGDLTQITPPSALGVQVRYEE---MMKMFGMKGYFCT--EIEQLQAAVKAANQL--TD 540
            ....:.|.           :|..:.|.:   ..:.||.:|:..|  |.|::...:|.|.:.  ..
 Frog   552 QVPMLGSN-----------VGCSLAYSDYHVAAEGFGGRGFLVTTQEEERISDIIKEAQEACHKG 605

  Fly   541 RPTIINVAISPSSDR 555
            :..:|||.|..::.|
 Frog   606 KAALINVLIGKTNFR 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hacl	NP_611460.1	PRK09259	8..552	CDD:236433	170/595 (29%)
		TPP_PYR_POX_like	8..161	CDD:132918	49/152 (32%)
		TPP_enzyme_M	195..322	CDD:278628	36/131 (27%)
		TPP_BZL_OCoD_HPCL	367..550	CDD:238962	55/189 (29%)
ilvbl	NP_001120212.1	IlvB	47..614	CDD:223107	169/592 (29%)
		TPP_PYR_POX_like	50..204	CDD:132918	50/153 (33%)
		TPP_enzyme_M	267..399	CDD:278628	36/133 (27%)
		TPP_BZL_OCoD_HPCL	441..614	CDD:238962	55/188 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000