Protein Alignment Efhc1.2 and efhc1

DIOPT Version :10

• Sequence 1: NP_611459.1
• Gene: Efhc1.2 / 37284
• FlyBaseID: FBgn0034487
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_957261.1
• Gene: efhc1 / 393942
• ZFINID: ZDB-GENE-040426-1300
• Length: 554
• Species: Danio rerio
• Alignment Length: 588
• Identity: 201/588 - (34%)
• Similarity: 297/588 - (50%)
• Gaps: 82/588 - (13%)

  Fly     6 GMPMLPGAQFYDRGKRRHPRQQTLMHYQGIQMLSDRREPELVEPNGIVADP--KCPPVPAQLNSL 68
            |:|.|||..|.|..|....|.|||....|   .:..|.|.:    ||..||  ......::.|.|
Zfish     8 GLPFLPGNTFRDLTKSAFHRAQTLDFKNG---YAQPRRPVV----GIGQDPLLSVNISHSERNQL 65

  Fly    69 WA--PKAT----------TKLPPWLAYDKQVLCFNAYFKENLTEIYHAPYQVRKVKIFFYLEDGT 121
            ..  |..|          ..:|...||||:||.|..||::.:...:...:::|.|..:::|||.:
Zfish    66 ITDIPNLTYGTDRSHLPLEFIPAHAAYDKKVLRFYGYFRQEVLHSWDEHFRIRPVVFYYHLEDDS 130

  Fly   122 MQVTEPKVENSGIPQGCLVHRQRIPKAPPTDREFISIF---DLNVDTDVQIFDRVYHISGCDVFT 183
            :.||||.|||||||||.|:.|||:.|.|..|     ::   ||||..|:.:|..||.|:.||.||
Zfish   131 ICVTEPPVENSGIPQGKLIKRQRLSKNPRGD-----LYHWKDLNVGMDINLFGEVYRITHCDPFT 190

  Fly   184 RQFLNRAGIFVPEAQQEPCDPTTEIRKRSGLKQTGNTATSALP--KKHAFAQFLEFDRRVLKFQG 246
            :.|:...||.:.|.:..|.||.|       .::..|..|...|  ..|...:||..||:||:|..
Zfish   191 QDFMESQGIVLNEFESIPSDPYT-------ARRAHNQQTHITPYDHNHQLERFLALDRQVLRFFA 248

  Fly   247 YWNDR-SEFGDVRKLEVCYYLADDTIDIKEKFPRNSGREGPTTFLKRGKLPKEFSGL--PLPGQQ 308
            .|:|. |.:|:.|.:.:.|||.||:::|.|....||||:.....|:|.|:||.....  |.|.
Zfish   249 LWDDSDSLYGEKRPVTLHYYLVDDSVEICEHHEANSGRDPFPVLLRRQKIPKHIKPTCEPFPS-- 311

  Fly   309 TAMTLLNVLGNSMRDVRYVADPLNTGQKEVQHYTDQDLQIGAVLNVFGRSVVLTSCDQFTQSYYR 373
                  .||..|..||:             :::..||.::|..:|:.||..:|..||.||..||:
Zfish   312 ------CVLEVSPHDVK-------------EYFCPQDFRVGEEVNLMGRRFLLYDCDDFTHKYYQ 357

  Fly   374 EKYGIQEFSPQPIPERS--DIRPYTQGGMGSRRLPPYNGWGSHEDSEGNCITVEPKPPQADFKKL 436
            ..:......|..:..|:  ||:         |.:|||||:||.|||..||:::.|:||:.:..||
Zfish   358 HHHPDIPIKPFTVDTRTQQDIK---------RVIPPYNGFGSLEDSLQNCLSLIPQPPKKNVIKL 413

  Fly   437 FKYDGCILRFGAKLISA-IRDNGERDFVISYFLADDTLQIYETSRRNSGFLGGEFLKRARVPLPG 500
            .:.|..:||:.|:|.|. ..|.|.| |::|:.||||.:.|:|.|.||||.:||:||::.|:|.||
Zfish   414 LENDHKVLRYAARLDSQNPLDEGRR-FILSFHLADDMISIFEKSTRNSGIIGGKFLEKTRIPKPG 477

  Fly   501 QDMYSSSRPEYYRANDFYIGRTMTLKDHIFHIVSADEFTLMYMEQHPSEFPVADIQKIMQKIREA 565
            .   ::.:||||:..|..:|.|:.:..|.|.:..||.|.|.::|....:.|    :..:..:|.|
Zfish   478 S---TAEKPEYYQPADLCVGATVEVFGHRFVVTDADRFVLSFLESQSHQTP----EHTLSSLRHA 535

  Fly   566 VRP 568
            ..|
Zfish   536 TDP 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efhc1.2	NP_611459.1	DM10	84..191	CDD:128921	46/109 (42%)
		DM10_dom	231..368	CDD:461948	44/139 (32%)
		DM10	440..547	CDD:128921	44/107 (41%)
efhc1	NP_957261.1	DM10_dom	86..190	CDD:461948	46/108 (43%)
		DM10_dom	233..352	CDD:461948	44/139 (32%)
		DM10_dom	410..513	CDD:461948	43/106 (41%)