Protein Alignment Efhc1.2 and efhc-1

DIOPT Version :10

• Sequence 1: NP_611459.1
• Gene: Efhc1.2 / 37284
• FlyBaseID: FBgn0034487
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_509738.2
• Gene: efhc-1 / 190059
• WormBaseID: WBGene00013028
• Length: 447
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 135/544 - (24%)
• Similarity: 218/544 - (40%)
• Gaps: 133/544 - (24%)

  Fly    24 PRQQTLMHYQGIQMLSDRREPELVEPNGIVADPKC-PPVPAQLNSLWAPKATT-----KLPPWL- 81
            |.:..|.|: |......||..:|...||     :| .||...:::.  ||..:     ...|.|
 Worm    14 PTEDILEHF-GSDPTPVRRRQQLKYKNG-----ECFVPVETIVDNY--PKQRSFHHYCNAGPLLH 70

  Fly    82 ---AYDKQVLCFNAYFKEN-LTEIYHAPYQVRKVKIFFYLEDGTMQVTEPKVENSGIPQGCLVHR 142
               |.:..||.|:||.:|: |.|..|   ::|..||.::|.|.|:.|.||.|:|:|...|.:..|
 Worm    71 EAEAANSAVLSFDAYAEEDGLDEEIH---RIRIFKINYHLNDDTITVNEPFVDNTGYLHGRIFRR 132

  Fly   143 QRIPKAPPTDREFISIFDLNVDTDVQIFDRVYHISGCDVFTRQFLNRAGIFVPEAQQEPCDPTTE 207
            |::|......:.::...||||.||:.:|..:|.|:.||.|||.||...|..|.|.::.|.||.
 Worm   133 QKVPAHNRIGKPYVHWSDLNVGTDINLFQTIYRITSCDTFTRSFLEEHGTKVNEDEELPEDPW-- 195

  Fly   208 IRKRSGLKQTGNTATSALPKKHAFAQFLEFDRR--VLKFQGYWNDR-SEFGDVRK---LEVCYYL 266
            :.:|.|..:|    ...||.:.      ||..|  :|.::..|.|. ::|...|.   .::..|.
 Worm   196 LVRRRGAPRT----APKLPDQR------EFINRPPMLVYRCCWLDHMNDFHGCRMKRIFKMYVYC 250

  Fly   267 ADDTIDIKEKFPRNSGREGPTTFLKRGKLPKEFSGLPLPGQQTAMTLLNVLGNSMRDVRYVADPL 331
            :|.|:.:.|:.....|:    .||||       ..||.|.|...:         .||.|:
 Worm   251 SDHTVALIEETKEFEGQ----LFLKR-------IALPFPVQPDMV---------KRDYRW----- 290

  Fly   332 NTGQKEVQHYTDQDLQIGAVLNVFGRSVVLTSC-DQFTQSYYREKYGIQEFSPQPIPERSDIRPY 395
                        .|::.|..::||.|.:.:..| :..|:|:.|:::|..:|:
 Worm   291 ------------WDIRPGVWVDVFCRPMFVFECANDETKSFTRQQFGETDFA------------- 330

  Fly   396 TQGGMGSRRLPPYNGWGSHEDSEGNCITVEPKPPQADFKKLFKYDGCILRFGAKLISAIRDNGER 460
                          .:.|....||        ||...|..    ...||:|...::.|.......
 Worm   331 --------------NYSSQILEEG--------PPTTQFFN----SPSILKFRCTMVDAPSVLYGL 369

  Fly   461 DFVISYFLADDTLQIYETSRRNSGFLGGEFLKRARVPLPGQDMYSSSRPEYYRANDFYIGRTMTL 525
            .|::.|.:....:.|.|..|: :...|..|||         |:.:|:    :..|.|..||.:..
 Worm   370 HFLLYYDVNRRIVNINEEGRK-TWTDGRVFLK---------DVDAST----FSENQFAPGRILQF 420

  Fly   526 KDHIFHIVSADEFTLMYM--EQHP 547
            ....|::|.:...|..|:  :|.|
 Worm   421 FKWRFNLVQSSGETGKYLRWKQTP 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efhc1.2	NP_611459.1	DM10	84..191	CDD:128921	41/107 (38%)
		DM10_dom	231..368	CDD:461948	30/143 (21%)
		DM10	440..547	CDD:128921	24/108 (22%)
efhc-1	NP_509738.2	DM10	76..181	CDD:128921	41/107 (38%)