DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and RLP3

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_173168.1	Gene:	RLP3 / 838296	AraportID:	AT1G17250	Length:	756	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	106/475 - (22%)
Similarity:	173/475 - (36%)	Gaps:	111/475 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TILHWSYLNFK-DVPMDLFLYEDLEEVYLKENFIS-VIPKWLLNITTLKFIHLAGNNL-SELPVD 65
            ::|...:.|.. ::|.|::...:||:::|..|.:| .|...:.::|.||.:.|..|:| .|:|:|
plant   254 SVLQAGFNNISGEIPSDIYNLSELEQLFLPVNHLSGKINDDITHLTKLKSLELYSNHLGGEIPMD 318

  Fly    66 IYMLENLEFLDVS-NNELKELPPTLGLLLNLQQLNVSGNQL--TELPVELSGLRNLEHLNIGKNQ 127
            |..|..|:.|.:. ||....:||:|....||.:||:..|:|  |...::.|..::|..|::|.|.
plant   319 IGQLSRLQSLQLHINNITGTVPPSLANCTNLVKLNLRLNRLEGTLSELDFSRFQSLSILDLGNNS 383

  Fly   128 FR-RLPVQLSECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLPAAL--------- 182
            |. ..|.::..|..|:.:..:.|:....|...:..|..|..|:.....|:.:..||
plant   384 FSGDFPWRVHSCKSLSAMRFASNKLTGQISPHVLELESLSILSLSDNKLMNITGALGILQGCRNL 448

  Fly   183 ------SKFMN----------------HVRIF---------------------------HNTAIN 198
                  ..|.|                :::||                           ||..:.
plant   449 STLLIGKNFYNETFPSDKDLISSDGFPNLQIFASGGSGLRGEIPAWLIKLKSLAVIDLSHNQLVG 513

  Fly   199 YIPMVYERFYQNFYDNRQRNTPVAVHRKGLFWVREL------ETSTR--LLLPVGT--------- 246
            .||.....|...||.:...|.......|.||.::.|      :.:.|  |.|||..
plant   514 SIPGWLGTFPHLFYIDLSENLLSGELPKDLFQLKALMSQKAYDATERNYLKLPVFVSPNNVTTHQ 578

  Fly   247 --RTVFPVP--------SVENRVSLYDDCLHALQTLNRFTPVYENVAMHRL-----LPEPYISSH 296
              ..:|.:|        :::..:.:....|..|..|.........:..|.|     |....:|::
plant   579 QYNQLFSLPPGIYIRRNNLKGSIPIEVGQLKVLHVLELSHNYLSGIIPHELSKLTSLERLDLSNN 643

  Fly   297 INNGPIARCTNSTCSRCLYTSYYFMVVKR-------RGSTSKQLFTCNFCTN--RCGLLWLTSND 352
            ..:|.|.....|     |:...||.||..       .||........||..|  .||.:.|||..
plant   644 HLSGRIPWSLTS-----LHYMSYFNVVNNSLDGPIPTGSQFDTFPQANFKGNPLLCGGILLTSCK 703

  Fly   353 KKYYQLAWRVSDDDDDDEEE 372
            ......|...:..|.:||||
plant   704 ASTKLPATTTNKADTEDEEE 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	4/21 (19%)
		LRR_8	26..82	CDD:290566	21/58 (36%)
		leucine-rich repeat	26..48	CDD:275380	6/22 (27%)
		LRR	<43..>194	CDD:227223	46/213 (22%)
		LRR_4	47..87	CDD:289563	15/41 (37%)
		leucine-rich repeat	49..71	CDD:275380	10/22 (45%)
		leucine-rich repeat	72..95	CDD:275380	7/23 (30%)
		leucine-rich repeat	96..117	CDD:275380	6/22 (27%)
		leucine-rich repeat	118..140	CDD:275380	7/22 (32%)
		leucine-rich repeat	141..164	CDD:275380	4/22 (18%)
RLP3	NP_173168.1	leucine-rich repeat	325..348	CDD:275380	7/22 (32%)
		leucine-rich repeat	374..397	CDD:275380	7/22 (32%)
		leucine-rich repeat	398..447	CDD:275380	9/48 (19%)
		leucine-rich repeat	448..500	CDD:275380	4/51 (8%)
		leucine-rich repeat	501..524	CDD:275380	5/22 (23%)
		leucine-rich repeat	525..546	CDD:275380	6/20 (30%)
		leucine-rich repeat	611..634	CDD:275380	4/22 (18%)
		leucine-rich repeat	635..658	CDD:275380	6/27 (22%)
		PLN00113	37..>709	CDD:215061	100/459 (22%)
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..172	CDD:275380
		leucine-rich repeat	177..203	CDD:275380
		leucine-rich repeat	204..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		leucine-rich repeat	253..276	CDD:275380	4/21 (19%)
		leucine-rich repeat	277..300	CDD:275380	6/22 (27%)
		leucine-rich repeat	301..324	CDD:275380	10/22 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000