DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11099 and LRRC2

DIOPT Version :9

Sequence 1:NP_001286627.1 Gene:CG11099 / 37282 FlyBaseID:FBgn0034485 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_078788.2 Gene:LRRC2 / 79442 HGNCID:14676 Length:371 Species:Homo sapiens


Alignment Length:177 Identity:61/177 - (34%)
Similarity:96/177 - (54%) Gaps:7/177 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 HWSYLNFKDVPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDIYMLEN 71
            ||:     ::|..|.....|.|.|:....|.:||.::.....::.:.|..|.:|.||.:|..|:|
Human   109 HWT-----ELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKN 168

  Fly    72 LEFLDVSNNELKELPPTLGLLLNLQQLNVSGN-QLTELPVELSGLRNLEHLNIGKNQFRRLPVQL 135
            |:.|:|..|.||.:||.||...||::|:.||| :|.|||.|||.|:.:..::|..|:|..:|:.:
Human   169 LKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICV 233

  Fly   136 SECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLPAAL 182
            .....|..|::|.|. |..:|:.|..|..|||....:..|.|||.::
Human   234 LRMSNLQWLDISSNN-LTDLPQDIDRLEELQSFLLYKNKLTYLPYSM 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11099NP_001286627.1 leucine-rich repeat 4..25 CDD:275380 4/17 (24%)
LRR_8 26..82 CDD:290566 18/55 (33%)
leucine-rich repeat 26..48 CDD:275380 6/21 (29%)
LRR <43..>194 CDD:227223 51/141 (36%)
LRR_4 47..87 CDD:289563 14/39 (36%)
leucine-rich repeat 49..71 CDD:275380 7/21 (33%)
leucine-rich repeat 72..95 CDD:275380 10/22 (45%)
leucine-rich repeat 96..117 CDD:275380 12/21 (57%)
leucine-rich repeat 118..140 CDD:275380 4/21 (19%)
leucine-rich repeat 141..164 CDD:275380 8/22 (36%)
LRRC2NP_078788.2 LRR 1 122..143 6/20 (30%)
leucine-rich repeat 123..145 CDD:275380 6/21 (29%)
LRR 2 145..166 6/20 (30%)
leucine-rich repeat 146..168 CDD:275380 7/21 (33%)
LRR_8 147..201 CDD:290566 23/53 (43%)
LRR_4 167..>201 CDD:289563 16/33 (48%)
LRR 3 168..189 11/20 (55%)
leucine-rich repeat 169..191 CDD:275380 10/21 (48%)
LRR 4 191..214 13/22 (59%)
leucine-rich repeat 192..215 CDD:275380 13/22 (59%)
LRR 5 215..235 4/19 (21%)
leucine-rich repeat 216..238 CDD:275380 4/21 (19%)
LRR_8 237..295 CDD:290566 15/44 (34%)
LRR 6 238..260 7/22 (32%)
leucine-rich repeat 239..261 CDD:275380 8/22 (36%)
LRR 7 261..283 7/19 (37%)
leucine-rich repeat 262..284 CDD:275380 7/18 (39%)
LRR 8 284..305
leucine-rich repeat 285..308 CDD:275380
LRR 9 308..329
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BICG
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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