DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and lrrc28

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_021333397.1	Gene:	lrrc28 / 555592	ZFINID:	ZDB-GENE-061128-1	Length:	366	Species:	Danio rerio

Alignment Length:	376	Identity:	101/376 - (26%)
Similarity:	163/376 - (43%)	Gaps:	75/376 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LHWSYLNFKDVPMDLFLYED---LEEVYLKENFISVIPKWLL-NITTLKFIHLAGNNLSELPVDI 66
            |..:|.|..:.|::|...|.   ||.:::|.|.::.:|:.|. .|..|..::|..||::.:|..|
Zfish    20 LFLNYRNLNNFPVELLKDEGMQFLERLFMKRNSLTTLPENLAQKIPNLIELYLHSNNIAIIPQAI 84

  Fly    67 YMLENLEFLDVSNNELKELPPTLGLLLNLQQLNVSGNQLTELPVELSGLRNLEHLNIGKNQFRRL 131
            ..|..|:.||:|:|.|:.:.|.:|.|.:|:.|.::.|||..||.||..||.||.|::..|..|.|
Zfish    85 GELVKLQSLDLSDNALQIICPEIGQLRSLRHLRLANNQLKFLPQELGDLRELETLDVSMNLLRTL 149

  Fly   132 PVQLSECVRLNELNVSDNEALVH-IPERISNLPMLQSLAADRCALVYLPAALSKFMNHVRIFHNT 195
            |.:|.:||.|..|....|  |:| :|.::..||.|..|:.....|..||..|.:.|.
Zfish   150 PERLHQCVSLQCLTADRN--LLHCLPRQLCLLPDLNELSMAANCLTSLPLDLGRSME-------- 204

  Fly   196 AINYIPMVYERFYQNFYDNRQ--RNTPVAVHRK-----GLFWVRELETSTRLLLPVGTRTVFPVP 253
             :.::          |.||..  :..|..::.|     |.....::....:|.|.:|..|| |:|
Zfish   205 -LQFV----------FVDNNAHLKGLPSYLYNKVIGCSGCGLALQISDVKQLCLTMGDVTV-PLP 257

  Fly   254 SVENRVSLYDD---------C--LHA-----LQTLNRFTPVYENVAMHRLLPEPYISSHINNGPI 302
            |....:....:         |  |||     .:.:...||.        |:|:..:.  :...|:
Zfish   258 SEVKAIGSESEQVLPLEELACRVLHAAYDWTCKDVKLRTPF--------LMPKSLLD--VVQWPL 312

  Fly   303 ARCTNSTCSRCLYTSYY----------FMVVKRRGSTSKQLFTCNFCTNRC 343
            ..|  ..||:.::|..|          ...|.||.:.|   |....|::||
Zfish   313 GHC--HRCSQPMFTIIYPKLFPLRETALAGVHRRSTVS---FVAYCCSSRC 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	5/18 (28%)
		LRR_8	26..82	CDD:290566	19/56 (34%)
		leucine-rich repeat	26..48	CDD:275380	7/22 (32%)
		LRR	<43..>194	CDD:227223	54/152 (36%)
		LRR_4	47..87	CDD:289563	13/39 (33%)
		leucine-rich repeat	49..71	CDD:275380	7/21 (33%)
		leucine-rich repeat	72..95	CDD:275380	9/22 (41%)
		leucine-rich repeat	96..117	CDD:275380	9/20 (45%)
		leucine-rich repeat	118..140	CDD:275380	9/21 (43%)
		leucine-rich repeat	141..164	CDD:275380	7/23 (30%)
lrrc28	XP_021333397.1	leucine-rich repeat	18..42	CDD:275380	6/21 (29%)
		leucine-rich repeat	43..66	CDD:275380	7/22 (32%)
		NEL	<46..>223	CDD:330839	61/197 (31%)
		leucine-rich repeat	67..89	CDD:275380	7/21 (33%)
		leucine-rich repeat	90..112	CDD:275380	9/21 (43%)
		leucine-rich repeat	113..135	CDD:275380	10/21 (48%)
		leucine-rich repeat	136..158	CDD:275380	9/21 (43%)
		leucine-rich repeat	159..181	CDD:275380	7/23 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333471at33208
OrthoFinder	1	1.000	-	-		FOG0004967
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010