DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and lrrc57

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001002627.1	Gene:	lrrc57 / 436900	ZFINID:	ZDB-GENE-040718-372	Length:	238	Species:	Danio rerio

Alignment Length:	162	Identity:	56/162 - (34%)
Similarity:	95/162 - (58%)	Gaps:	3/162 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DVPMDL-FLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDIYMLENLEFLDVS 78
            :.|.|| .|..:|..|.|..|.|..:|.::.:...||...::.|.|:.||.||..|:.||.|.::
Zfish    28 EFPEDLQKLTANLRTVDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILN 92

  Fly    79 NNELKELPPTLGLLLNLQQLNVSGNQLTELPVELSGLRNLEHLNIGKNQFRRLPVQLSECVRLNE 143
            .|:||:||.::|.|.:|:.|::||||..|.|..|..||.|:.|::.|||.|.:|.:::| ::..|
Zfish    93 GNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVPAEVAE-LQAIE 156

  Fly   144 LNVSDNEALVHIPERISNLPMLQSLAADRCAL 175
            :|::.|: :..:.:.:|..|.|:.|..:...|
Zfish   157 INLNQNQ-ISSVTQEVSRTPRLKVLRLEENCL 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	4/10 (40%)
		LRR_8	26..82	CDD:290566	19/55 (35%)
		leucine-rich repeat	26..48	CDD:275380	6/21 (29%)
		LRR	<43..>194	CDD:227223	46/133 (35%)
		LRR_4	47..87	CDD:289563	16/39 (41%)
		leucine-rich repeat	49..71	CDD:275380	9/21 (43%)
		leucine-rich repeat	72..95	CDD:275380	10/22 (45%)
		leucine-rich repeat	96..117	CDD:275380	9/20 (45%)
		leucine-rich repeat	118..140	CDD:275380	8/21 (38%)
		leucine-rich repeat	141..164	CDD:275380	4/22 (18%)
lrrc57	NP_001002627.1	LRR 1	10..36		3/7 (43%)
		LRR_RI	<37..191	CDD:238064	52/153 (34%)
		LRR 2	37..62		6/24 (25%)
		leucine-rich repeat	40..65	CDD:275380	7/24 (29%)
		LRR_8	62..119	CDD:290566	24/56 (43%)
		LRR 3	64..82		7/17 (41%)
		leucine-rich repeat	66..85	CDD:275380	7/18 (39%)
		LRR 4	83..106		10/22 (45%)
		leucine-rich repeat	86..108	CDD:275380	10/21 (48%)
		LRR 5	108..128		9/19 (47%)
		leucine-rich repeat	109..131	CDD:275380	10/21 (48%)
		LRR 6	129..152		10/23 (43%)
		leucine-rich repeat	132..154	CDD:275380	8/22 (36%)
		LRR 7	154..173		3/19 (16%)
		leucine-rich repeat	155..176	CDD:275380	4/21 (19%)
		LRR 8	174..199		4/14 (29%)
		leucine-rich repeat	177..198	CDD:275380	3/11 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910