DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and Sur-8

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster

Alignment Length:	174	Identity:	53/174 - (30%)
Similarity:	93/174 - (53%)	Gaps:	5/174 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LNFKD-----VPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDIYMLE 70
            ||.|:     :|:|:..:.::.|:.|..|.:..:|..::|:..|:.:.|:.|.|.::|..|..|.
  Fly   444 LNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLR 508

  Fly    71 NLEFLDVSNNELKELPPTLGLLLNLQQLNVSGNQLTELPVELSGLRNLEHLNIGKNQFRRLPVQL 135
            .|..||:..|.::.||..:|||..||:|.:..||:|.||..:..|.||.||::.:|..:.||.::
  Fly   509 KLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEI 573

  Fly   136 SECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLP 179
            .....|..|.::.|..|..:|..::....|:.|..|:|.|..:|
  Fly   574 GSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIP 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	5/18 (28%)
		LRR_8	26..82	CDD:290566	16/55 (29%)
		leucine-rich repeat	26..48	CDD:275380	5/21 (24%)
		LRR	<43..>194	CDD:227223	44/137 (32%)
		LRR_4	47..87	CDD:289563	12/39 (31%)
		leucine-rich repeat	49..71	CDD:275380	7/21 (33%)
		leucine-rich repeat	72..95	CDD:275380	9/22 (41%)
		leucine-rich repeat	96..117	CDD:275380	8/20 (40%)
		leucine-rich repeat	118..140	CDD:275380	6/21 (29%)
		leucine-rich repeat	141..164	CDD:275380	5/22 (23%)
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380
		leucine-rich repeat	185..207	CDD:275380
		LRR_RI	204..401	CDD:238064
		LRR_8	207..264	CDD:290566
		leucine-rich repeat	208..230	CDD:275380
		leucine-rich repeat	231..253	CDD:275380
		LRR_8	252..310	CDD:290566
		leucine-rich repeat	254..276	CDD:275380
		leucine-rich repeat	277..299	CDD:275380
		LRR_8	299..356	CDD:290566
		leucine-rich repeat	300..322	CDD:275380
		leucine-rich repeat	323..345	CDD:275380
		LRR_8	344..403	CDD:290566
		leucine-rich repeat	346..368	CDD:275380
		leucine-rich repeat	369..392	CDD:275380
		LRR_RI	<379..566	CDD:238064	40/121 (33%)
		leucine-rich repeat	417..440	CDD:275380
		leucine-rich repeat	441..486	CDD:275380	10/41 (24%)
		LRR_8	463..520	CDD:290566	16/56 (29%)
		leucine-rich repeat	487..507	CDD:275380	6/19 (32%)
		leucine-rich repeat	510..532	CDD:275380	9/21 (43%)
		LRR_8	532..588	CDD:290566	18/55 (33%)
		leucine-rich repeat	556..578	CDD:275380	6/21 (29%)
		leucine-rich repeat	603..626	CDD:275380	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467255
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840