DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and CG3494

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	60/193 - (31%)
Similarity:	94/193 - (48%)	Gaps:	23/193 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NKTILHWSYLNFKDVPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDI 66
            |..||..|.....:|||::|      |...:|         |:||     :.|.||.|.|:|.|:
  Fly    36 NTRILQVSKAQISEVPMEVF------EAAQQE---------LVNI-----VSLDGNRLLEMPKDL 80

  Fly    67 YML-ENLEFLDVSNNELKELPPTLGLLLNLQQLNVSGNQLTELPVELSGLRNLEHLNIGKNQFRR 130
            .:| |:|..|.::.|::..:|..:.....|..|::|.|.|.:||:||.|||.|.:|:|..|:||:
  Fly    81 PLLSEHLTQLVLNKNQISFVPTNISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQ 145

  Fly   131 LPVQLSECVRLNELNVSDNE--ALVHIPERISNLPMLQSLAADRCALVYLPAALSKFMNHVRI 191
            ||..:.|..||..|:..||:  |:......:..:..|:.|......:..:|..|.|..|.|.:
  Fly   146 LPRCIYELERLETLSAHDNQIRAIDASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVEL 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	7/20 (35%)
		LRR_8	26..82	CDD:290566	17/56 (30%)
		leucine-rich repeat	26..48	CDD:275380	5/21 (24%)
		LRR	<43..>194	CDD:227223	50/152 (33%)
		LRR_4	47..87	CDD:289563	12/40 (30%)
		leucine-rich repeat	49..71	CDD:275380	8/22 (36%)
		leucine-rich repeat	72..95	CDD:275380	4/22 (18%)
		leucine-rich repeat	96..117	CDD:275380	10/20 (50%)
		leucine-rich repeat	118..140	CDD:275380	9/21 (43%)
		leucine-rich repeat	141..164	CDD:275380	5/24 (21%)
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	60/193 (31%)
		leucine-rich repeat	38..62	CDD:275380	9/38 (24%)
		leucine-rich repeat	63..86	CDD:275380	10/27 (37%)
		LRR_4	85..124	CDD:289563	10/38 (26%)
		leucine-rich repeat	87..109	CDD:275380	4/21 (19%)
		leucine-rich repeat	110..133	CDD:275380	12/22 (55%)
		leucine-rich repeat	134..155	CDD:275380	8/20 (40%)
		leucine-rich repeat	156..181	CDD:275380	5/24 (21%)
		leucine-rich repeat	182..204	CDD:275380	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467251
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930