DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and CG10307

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001286690.1	Gene:	CG10307 / 37477	FlyBaseID:	FBgn0034655	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	118/277 - (42%)	Gaps:	50/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LHWSYLNFKDVPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDIYMLE 70
            |:.|:....|||..:...|.|.:::|.:|.::.||..:.::..|:.:.|..|.|.|.|:.|..|.
  Fly    28 LNLSHYQISDVPGIIEKCETLMKLFLNQNKLTKIPSSIGSLMRLQVLTLDYNKLDEFPLCICRLV 92

  Fly    71 NLEFLDVSNNELKELPPTLGLLLNLQQLNVSGNQLTELPVELSGLRNLEHLNIGKNQFRRLPVQL 135
            .|:||::|.|.:..|||.||.|..|:....:...|.|||.|:....:||.|.:..|..::|
  Fly    93 RLKFLNISCNNISSLPPELGYLTQLETFWCNNTGLLELPNEIRNCEHLETLGVRGNPLKKL---- 153

  Fly   136 SECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLPAALSKFMNHVRIFHNTAINYI 200
                                |:.|..|..|:.|.|:.|.|..:|..::...|.|.:
  Fly   154 --------------------PDAIGALSSLRWLTAEGCELSEVPLTMALLGNLVHL--------- 189

  Fly   201 PMVYERFYQNFYDNRQRNTP---VAVHRKGLFWVREL---ETSTRLLLPVGTRTVFPVPSVENRV 259
                     |...||.|..|   :|:.:....::.|.   |..||..|. ..||:..:...:|.:
  Fly   190 ---------NLKGNRLRRLPRMLMAMQKLRFAFLNENCIDEMPTRSQLE-ELRTLHMLNLSKNPI 244

  Fly   260 SLYDDC-LHALQTLNRF 275
            ||:.|. |.||:..|.:
  Fly   245 SLHRDLQLMALRQTNLY 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	5/18 (28%)
		LRR_8	26..82	CDD:290566	18/55 (33%)
		leucine-rich repeat	26..48	CDD:275380	5/21 (24%)
		LRR	<43..>194	CDD:227223	41/150 (27%)
		LRR_4	47..87	CDD:289563	14/39 (36%)
		leucine-rich repeat	49..71	CDD:275380	8/21 (38%)
		leucine-rich repeat	72..95	CDD:275380	11/22 (50%)
		leucine-rich repeat	96..117	CDD:275380	5/20 (25%)
		leucine-rich repeat	118..140	CDD:275380	5/21 (24%)
		leucine-rich repeat	141..164	CDD:275380	3/22 (14%)
CG10307	NP_001286690.1	leucine-rich repeat	27..44	CDD:275380	5/15 (33%)
		LRR_8	47..104	CDD:290566	18/56 (32%)
		leucine-rich repeat	48..70	CDD:275380	5/21 (24%)
		LRR	69..>244	CDD:227223	55/217 (25%)
		leucine-rich repeat	71..93	CDD:275380	8/21 (38%)
		leucine-rich repeat	94..116	CDD:275380	11/21 (52%)
		leucine-rich repeat	117..139	CDD:275380	6/21 (29%)
		leucine-rich repeat	140..162	CDD:275380	8/45 (18%)
		leucine-rich repeat	163..185	CDD:275380	6/21 (29%)
		leucine-rich repeat	186..208	CDD:275380	7/39 (18%)
		leucine-rich repeat	209..233	CDD:275380	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467250
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930