DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and Lrrc2

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_006243988.1	Gene:	Lrrc2 / 301033	RGDID:	1311716	Length:	379	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	63/182 - (34%)
Similarity:	101/182 - (55%)	Gaps:	2/182 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NKTILHWSYLNFKDVPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDI 66
            |..:...|...:|::|..|.....|:|.::....|.:||.::....::|.:.|..|.::.||.:|
  Rat   107 NPFVFELSGTQWKELPDSLKEQTHLKEWHIHNTLIQIIPTYIELFHSMKILDLPKNQITCLPPEI 171

  Fly    67 YMLENLEFLDVSNNELKELPPTLGLLLNLQQLNVSGN-QLTELPVELSGLRNLEHLNIGKNQFRR 130
            ..|:||:.|:||.|.||.:||.||...||::|:.||| .|.|||.|||.|:.:..::|..|:|..
  Rat   172 GRLKNLKELNVSFNHLKSIPPELGDCENLERLDCSGNLDLMELPFELSNLKQVTFVDISANKFSS 236

  Fly   131 LPVQLSECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLPAAL 182
            :|:.:....||..|::|.|: |..:|:.|..|..||.....:..|.|||.|:
  Rat   237 VPICVLRMCRLQWLDISSND-LTDLPQDIDRLEELQGFLLYKNKLTYLPQAM 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	4/20 (20%)
		LRR_8	26..82	CDD:290566	18/55 (33%)
		leucine-rich repeat	26..48	CDD:275380	5/21 (24%)
		LRR	<43..>194	CDD:227223	53/141 (38%)
		LRR_4	47..87	CDD:289563	15/39 (38%)
		leucine-rich repeat	49..71	CDD:275380	7/21 (33%)
		leucine-rich repeat	72..95	CDD:275380	11/22 (50%)
		leucine-rich repeat	96..117	CDD:275380	12/21 (57%)
		leucine-rich repeat	118..140	CDD:275380	4/21 (19%)
		leucine-rich repeat	141..164	CDD:275380	8/22 (36%)
Lrrc2	XP_006243988.1	leucine-rich repeat	131..153	CDD:275380	5/21 (24%)
		LRR_8	153..209	CDD:290566	24/55 (44%)
		leucine-rich repeat	154..176	CDD:275380	7/21 (33%)
		LRR_4	175..>209	CDD:289563	17/33 (52%)
		leucine-rich repeat	177..199	CDD:275380	11/21 (52%)
		leucine-rich repeat	200..223	CDD:275380	13/22 (59%)
		leucine-rich repeat	224..245	CDD:275380	4/20 (20%)
		LRR_8	246..303	CDD:290566	16/43 (37%)
		leucine-rich repeat	247..269	CDD:275380	8/22 (36%)
		leucine-rich repeat	270..292	CDD:275380	7/18 (39%)
		leucine-rich repeat	293..316	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910