DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11099 and lrrc2

DIOPT Version :9

Sequence 1:	NP_001286627.1	Gene:	CG11099 / 37282	FlyBaseID:	FBgn0034485	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_002940651.1	Gene:	lrrc2 / 100486200	XenbaseID:	XB-GENE-962135	Length:	366	Species:	Xenopus tropicalis

Alignment Length:	178	Identity:	55/178 - (30%)
Similarity:	99/178 - (55%)	Gaps:	7/178 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 HWSYLNFKDVPMDLFLYEDLEEVYLKENFISVIPKWLLNITTLKFIHLAGNNLSELPVDIYMLEN 71
            ||     :::|..|.....|:::::....|..||.::.....|..:.|:.|.:..||.:|..|.|
Frog   105 HW-----EELPDSLREQTHLKQLHVNNTRIQTIPDYIQLFQKLIVLDLSHNKIRCLPPEIGYLAN 164

  Fly    72 LEFLDVSNNELKELPPTLGLLLNLQQLNVSGN-QLTELPVELSGLRNLEHLNIGKNQFRRLPVQL 135
            |:..::|.|.|:.:||.||...||::|::||| :|||||.|||.|:.:..:::..|:|..:|:.:
Frog   165 LKEFNISFNNLQIIPPELGNCENLEKLDLSGNLELTELPFELSSLKKVTFVDVSANKFSSIPICV 229

  Fly   136 SECVRLNELNVSDNEALVHIPERISNLPMLQSLAADRCALVYLPAALS 183
            .....|..|::|.|: |..:|:.|..|..|::|...:..:.||.|.::
Frog   230 LRMSSLQWLDISSNK-LQDLPQDIDRLEELETLMLQKNKITYLSAEIT 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11099	NP_001286627.1	leucine-rich repeat	4..25	CDD:275380	4/17 (24%)
		LRR_8	26..82	CDD:290566	15/55 (27%)
		leucine-rich repeat	26..48	CDD:275380	4/21 (19%)
		LRR	<43..>194	CDD:227223	47/142 (33%)
		LRR_4	47..87	CDD:289563	12/39 (31%)
		leucine-rich repeat	49..71	CDD:275380	7/21 (33%)
		leucine-rich repeat	72..95	CDD:275380	8/22 (36%)
		leucine-rich repeat	96..117	CDD:275380	13/21 (62%)
		leucine-rich repeat	118..140	CDD:275380	3/21 (14%)
		leucine-rich repeat	141..164	CDD:275380	8/22 (36%)
lrrc2	XP_002940651.1	LRR	103..>314	CDD:227223	55/178 (31%)
		leucine-rich repeat	119..141	CDD:275380	4/21 (19%)
		leucine-rich repeat	142..164	CDD:275380	7/21 (33%)
		leucine-rich repeat	165..187	CDD:275380	8/21 (38%)
		leucine-rich repeat	188..211	CDD:275380	14/22 (64%)
		leucine-rich repeat	212..234	CDD:275380	3/21 (14%)
		leucine-rich repeat	235..257	CDD:275380	8/22 (36%)
		leucine-rich repeat	258..280	CDD:275380	5/19 (26%)
		leucine-rich repeat	281..303	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000