DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11044 and AMN1

DIOPT Version :9

Sequence 1:	NP_611456.1	Gene:	CG11044 / 37281	FlyBaseID:	FBgn0034484	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_009716.1	Gene:	AMN1 / 852455	SGDID:	S000000362	Length:	549	Species:	Saccharomyces cerevisiae

Alignment Length:	147	Identity:	38/147 - (25%)
Similarity:	56/147 - (38%)	Gaps:	32/147 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 KAWRNVKKTNPRL-------RVHLRLENLTDGEVVLQPEAPVHSITYCAPQ-TRIRAELLVRMVD 375
            :.|.||  |.|.|       .||...|.|...:...|...|.|.|.:...| |:...|.|.||..
Yeast   249 RLWLNV--TRPFLFKSLHFKSVHNFKEFLRTSQETTQVMRPSHFILHKLHQVTQPDIERLSRMEC 311

  Fly   376 HYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCRQCFNVDTLII--REKVSTSTLLLIAKTAK 438
            .....|..|   :.||.:.|..:...:..|           :.|||  .:.:..:.||.::::..
Yeast   312 QNLKWLEFY---VCPRITPPLSWFDNLHKL-----------EKLIIPGNKNIDDNFLLRLSQSIP 362

  Fly   439 NLQHLHVRRFAVILRCD 455
            ||:||      |:..||
Yeast   363 NLKHL------VLRACD 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689
AMN1	NP_009716.1	AMN1	285..509	CDD:187754	27/109 (25%)
		leucine-rich repeat	314..337	CDD:275381	5/25 (20%)
		leucine-rich repeat	338..363	CDD:275381	6/35 (17%)
		leucine-rich repeat	364..389	CDD:275381	6/16 (38%)
		leucine-rich repeat	390..417	CDD:275381
		leucine-rich repeat	418..443	CDD:275381
		leucine-rich repeat	444..471	CDD:275381
		leucine-rich repeat	472..493	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900