DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11044 and fbxl8

DIOPT Version :9

Sequence 1:	NP_611456.1	Gene:	CG11044 / 37281	FlyBaseID:	FBgn0034484	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001032499.2	Gene:	fbxl8 / 641481	ZFINID:	ZDB-GENE-051120-81	Length:	367	Species:	Danio rerio

Alignment Length:	408	Identity:	93/408 - (22%)
Similarity:	154/408 - (37%)	Gaps:	104/408 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LPDLVLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLTKPKFNYYSGWQFCLDH 118
            ||:.:|..||::|..:::..|.:||:.|......|:.|.:..|...:.|.....|
Zfish     3 LPEEILAHIFSFLPLQDKCNAFIVCKAWSNIMTHPSSWKDTEVRCESGTSVPDRY---------- 57

  Fly   119 MRTQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLTWNIDKGREVNPDTQFIGIGSRIRTLVYHF 183
                   |.:...||.::.|  .|..:.....|.| |.:.:.        ..|...|:..|  ..
Zfish    58 -------SDLLPLVRNLKLR--ISLTDPANRKTAL-WVLQQA--------VAGGDGRLEGL--SI 102

  Fly   184 PCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDL--HTLKLVDFVLERYEANHLLDEVVCS-- 244
            .|..:.|       ||..|..|.:.|.::|...:.|  ..||.|.|.|.        |..|.|
Zfish   103 CCVANTP-------LFYAGQDLQQGLVDILTNGSSLTIFDLKGVPFTLS--------DSFVRSVA 152

  Fly   245 -CCTKMR---------VLNLVNVTTMH----CPIMHVGLFLNLQVLTISPQNIDDDV---LSLLA 292
             .|..::         |..:.:.|..|    ||        :|.||.:...::..||   |.|..
Zfish   153 MLCPALKSLYINNQSLVCGVTSETLRHVLKSCP--------SLNVLGVFQASLSQDVFQDLMLPE 209

  Fly   293 DTKLRHLHLLQNCYTPSHLTISACGVKAWRNVKKTNPRLRVHLRLEN-LTDGEV--VLQPEAPVH 354
            ...|:.|.|  .|......|:..|. :.|..||:.:|||.|.|.|:: |.:..|  ||||..||.
Zfish   210 RPALKKLEL--RCERSLKYTVPLCD-QIWLEVKRRHPRLCVELELDHTLPELHVPGVLQPSIPVR 271

  Fly   355 SI-----TYCAPQTRIRAELLVRMVDHYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCRQCF 414
            .:     |....:.||..:.       |..||.|...:.:|   ||:     ::|.::::.::|.
Zfish   272 CLRLLTWTLLLDEVRIVGQC-------YADTLEVLELQTVP---SPE-----LNSELIVLAQRCV 321

  Fly   415 NVDTL----IIREKVSTS 428
            .:..:    ::.::|.|:
Zfish   322 RLQEVHCYCVVSQEVITA 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689	12/39 (31%)
fbxl8	NP_001032499.2	F-box-like	2..41	CDD:289689	11/37 (30%)
		leucine-rich repeat	131..157	CDD:275381	10/33 (30%)
		leucine-rich repeat	158..186	CDD:275381	5/35 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1216869at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920