Protein Alignment CG11044 and FBXL8

DIOPT Version :9

• Sequence 1: NP_611456.1
• Gene: CG11044 / 37281
• FlyBaseID: FBgn0034484
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_060848.2
• Gene: FBXL8 / 55336
• HGNCID: 17875
• Length: 374
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 101/441 - (22%)
• Similarity: 143/441 - (32%)
• Gaps: 166/441 - (37%)

  Fly    54 LPDLVLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLV----DDRTLTKPKFNYYSGWQF 114
            ||:.||..||.:|:.::|..|..|||.|..|.....||::..:    :...:..|   |.|.
Human     8 LPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCECELEGMLPP---YLSA--- 66

  Fly   115 CLDH---MRTQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLTWNIDKGREVNPDTQFIGIGSRI 176
            ||||   :|.:|..||          :|  |.....:.:.:|.                |....:
Human    67 CLDHIHNLRLEFEPSR----------KP--SRRAAIELLMVLA----------------GRAPGL 103

  Fly   177 RTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDFVLERYEANHLLDEV 241
            |.|  ...|...:|       ||..|..:|                          ||.|    .
Human   104 RGL--RLECRGEKP-------LFDAGRDVL--------------------------EAVH----A 129

  Fly   242 VCSCCTKMRVLN-----------LVNVTTMHCPIMHVGLFLNLQVL--TISPQNIDDDVLSLL-A 292
            ||...:::|.|:           ||......||.:| .|||:...|  ::.|    ..||.|| |
Human   130 VCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELH-SLFLDNSTLVGSVGP----GSVLELLEA 189

  Fly   293 DTKLR--HLHLLQ----------------------NCYTPSHLTISACGVKAWRNVKKTNPRLRV 333
            ..:||  .|||..                      .|..|.....|....:||..:::.:|.|.|
Human   190 CPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASPLPNEAWVALRRRHPGLAV 254

  Fly   334 HLRLENLTDGEV---VLQPEAPV---------------------HSITYCAPQTRIRA------- 367
            .|.||.....|.   ||||..||                     ::.|.||.:.|..|
Human   255 ELELEPALPAESVTRVLQPAVPVAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAA 319

  Fly   368 --ELLVRMVD----HYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCRQ 412
              ||..|...    |   ...|..|.:|..|.:..|   |:.:..|.:.|:
Human   320 LEELAARCAALREVH---CFCVVSHSVLDAFRAHCP---RLRTYTLKLTRE 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689	16/39 (41%)
FBXL8	NP_060848.2	leucine-rich repeat	103..136	CDD:275381	13/71 (18%)
		LRR_RI	<132..>212	CDD:330982	22/84 (26%)
		leucine-rich repeat	137..163	CDD:275381	5/25 (20%)
		leucine-rich repeat	164..192	CDD:275381	11/32 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1216869at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920