DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11044 and CG12402

DIOPT Version :9

Sequence 1:	NP_611456.1	Gene:	CG11044 / 37281	FlyBaseID:	FBgn0034484	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001303481.1	Gene:	CG12402 / 41714	FlyBaseID:	FBgn0038202	Length:	671	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	83/378 - (21%)
Similarity:	139/378 - (36%)	Gaps:	111/378 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 DHMRTQFCLSRIGRYVRGIEFRPW-HSFNNIFQFMTMLTWNIDKGREVNPDTQFIGIGSRIRTLV 180
            ||..|..|::.......||:.|.| .:|.|:....|:         :::.:...:.:.:.:|.:.
  Fly   271 DHAETLVCVNLFFSCSPGIDTREWCRAFENMHNLRTL---------KLSGNCHLVLLEAVLRAVP 326

  Fly   181 YHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTD--LHTLKLVDFVL-ERYEANHLLDEVV 242
            ...|..          :|..||  :|.:..||||.:..  ..|||::|.:. .:..||
  Fly   327 ESAPIR----------QLDLTG--MLSLTNELLLYVAGKWQSTLKVLDLMFCVQLNAN------- 372

  Fly   243 CSCCTKMRVLN--LVNVTTMHC-PIMHVGLFLNLQVLTISPQNIDDDVLSLLADTKLRHLHLLQN 304
              |...:|.|:  |..:|..:| .:...||.          |.:..|:     :..|:.|||.:.
  Fly   373 --CIDALRQLSGRLEALTMAYCRELTGTGLL----------QGLAGDI-----NYSLQELHLEET 420

  Fly   305 CYTPSHLTISACGVKAWRNVKKTNPRLRVHLRLEN----LTDGEVVLQPEAPVHSITYCAPQTRI 365
            .:....   |.|      .:.:..|.|| .|.|:|    :||..:.          |.|..|||:
  Fly   421 IFLDES---SMC------QLLERLPNLR-RLSLDNCRQAVTDRTMA----------TICQYQTRL 465

  Fly   366 R---AELLVRMVDHYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCRQCFNVDTLIIREKVST 427
            |   .|..:::.|   ..|..||       .:|.|. ||:..|..|..|.|.||          |
  Fly   466 RNLNIEYCMKITD---QGLMGYG-------DTPYPI-SRLRGLKELNLRGCRNV----------T 509

  Fly   428 STLLLIAKTAKNLQHLHVRRFAVILRCDWPRHPEWSNEFYAWLKRNSRSYEAV 480
            .:.|::......|:.|.:.      .|:     ..::|.:..|.:|..|.||:
  Fly   510 DSSLMVGLKLPELRALSLG------YCN-----RLTSEGFEALTQNCPSLEAL 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689
CG12402	NP_001303481.1	F-box	75..117	CDD:279040
		leucine-rich repeat	281..303	CDD:275381	6/21 (29%)
		LRR_RI	<297..482	CDD:238064	51/252 (20%)
		leucine-rich repeat	304..330	CDD:275381	2/34 (6%)
		leucine-rich repeat	331..357	CDD:275381	8/37 (22%)
		leucine-rich repeat	358..379	CDD:275381	6/29 (21%)
		leucine-rich repeat	384..409	CDD:275381	7/39 (18%)
		leucine-rich repeat	412..437	CDD:275381	6/33 (18%)
		AMN1	430..595	CDD:187754	40/165 (24%)
		leucine-rich repeat	438..464	CDD:275381	10/36 (28%)
		leucine-rich repeat	465..496	CDD:275381	10/41 (24%)
		leucine-rich repeat	497..521	CDD:275381	8/33 (24%)
		leucine-rich repeat	522..547	CDD:275381	6/35 (17%)
		leucine-rich repeat	548..573	CDD:275381	2/4 (50%)
		leucine-rich repeat	574..599	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900