DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11044 and Kdm2

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster


Alignment Length:435 Identity:86/435 - (19%)
Similarity:127/435 - (29%) Gaps:204/435 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 LPDLVLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLTKPKFNYYSGWQFCLDH 118
            |...||:.||.||..........||:.|..|...|.:|.            |.|       |.:|
  Fly  1065 LDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWK------------KMN-------CSEH 1110

  Fly   119 MRTQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLTWNIDKGREVNPDTQFIGIGSRIRTLVYHF 183
            ..:...|:.|      :..:|.|         .:|.|           ||.              
  Fly  1111 KMSASLLTAI------VRRQPEH---------LILDW-----------TQI-------------- 1135

  Fly   184 PCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDFVLERYEANHLLDEVVCSCCTK 248
                                 ..|.|..|:.||..|..|.|                        
  Fly  1136 ---------------------AKRQLAWLVARLPALKNLSL------------------------ 1155

  Fly   249 MRVLNLVNVTTMHCPI-----MHVGLFLNLQVLTIS-PQNIDD----DVLSLLAD---------T 294
                       .:|||     :|..|...||.|.:| .:.::|    |:||...|         |
  Fly  1156 -----------QNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKT 1209

  Fly   295 KLRHLHLLQNCYTPSHLTISACGVKAWRNVKKTNPRLRVHLRL---ENLTDGEVVLQPEAPVHSI 356
            :||.|.:::...|    .||...|   |.:.::.|.|| ||.|   :.:||..|     |.:.: 
  Fly  1210 RLRDLKVMKLAGT----DISDVAV---RYITQSLPYLR-HLDLSSCQRITDAGV-----AQIGT- 1260

  Fly   357 TYCAPQTRIRAELLVRMVDHYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCR---------- 411
                                  ||.|.                :|:..|.|..||          
  Fly  1261 ----------------------STTAT----------------ARLTELNLSACRLVSENALEHL 1287

  Fly   412 -QCFNVDTLIIRE--KVSTSTLLLIAKTAKNLQHLHVRRFAVILR 453
             :|..:..|.:|.  :|||.:::..|..:|:  .|.||...::.|
  Fly  1288 AKCEGLIWLDLRHVPQVSTQSVIRFASNSKH--DLCVRDIKLVER 1330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 13/39 (33%)
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 12/53 (23%)
leucine-rich repeat 1102..1125 CDD:275381 7/47 (15%)
leucine-rich repeat 1126..1149 CDD:275381 10/77 (13%)
leucine-rich repeat 1150..1173 CDD:275381 8/57 (14%)
AMN1 1166..>1320 CDD:187754 46/207 (22%)
leucine-rich repeat 1174..1213 CDD:275381 11/38 (29%)
leucine-rich repeat 1214..1238 CDD:275381 6/30 (20%)
leucine-rich repeat 1239..1267 CDD:275381 12/72 (17%)
leucine-rich repeat 1268..1292 CDD:275381 5/23 (22%)
leucine-rich repeat 1293..1317 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.