DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11044 and fbxl6

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001296447.1 Gene:fbxl6 / 323163 ZFINID:ZDB-GENE-060810-162 Length:564 Species:Danio rerio


Alignment Length:513 Identity:94/513 - (18%)
Similarity:184/513 - (35%) Gaps:136/513 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 ELGLRRKSSAQLEVMQKAGWKIDGDEKACYIDVDEDEDQDTENMIES-------NW-RYLPDLVL 59
            ::|.::|::.:.:.......|.....|...:.|.|:.| |..::::|       :| :.||..:|
Zfish    90 KVGKKKKTNKKAKTKGSTSKKEKAPVKTEVLKVREETD-DKHDVMDSAKTDRFDHWGQSLPLEIL 153

  Fly    60 EQIFTYLTPKERYY-----AGLVCRQWYRAFYLPTVWNNFLVDDRTLTKPKFNYYSGWQFCLDHM 119
            .:||.:...::...     .|.|||.|..|...|.:|.:..:.                      
Zfish   154 VKIFQFAVFQDGAVPLLCRVGRVCRLWNGAASSPILWRSVSIG---------------------- 196

  Fly   120 RTQFCLSRIGR-YVRGIEFR-----PWHSFNNIFQF--MTMLTWNIDKGREVNPDTQFIGIGSRI 176
               :|....|: .:.|.|.:     .|.:.|.:||.  .::..|..:....:...:|..   ..:
Zfish   197 ---YCWIEPGKSQLPGTEQKIKNTVDWLAENRLFQLREFSLCHWKKNVDYVIQKVSQSC---LSL 255

  Fly   177 RTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDFVLERY--------- 232
            .:|...:...|::       |.|...|...:.|:::.::.::::...||.| ||.|         
Zfish   256 HSLKLSYCTGMTE-------KAFQNLGADCQSLEDINVQHSEINVDGLVSF-LEAYGNQIKKIYF 312

  Fly   233 ----EANHLLDEVVCSCCTKMRVLNL--------------VNVTTMHCPIMHVGLFLNLQVLTIS 279
                :::.||..:...||.::|:|.:              :....:.||.:.....:|   :|..
Zfish   313 THSTKSDKLLSALSKGCCPELRLLEINTKLDGGYSQLPICIQGLQIGCPKLQTFRLMN---VTAV 374

  Fly   280 PQNIDDDVLSLLADTKLRHLHLLQNCYTPSHLTISACGVKAWRNVKKTNPRLRV-HLRLENLTDG 343
            |:.|.:...|......|..|.:..:.:  |.:|.:..     .||...:|.||| .||      |
Zfish   375 PKMIRNIPSSTCGFPMLEELCIATSFH--SFMTDNDL-----NNVLHGSPNLRVLDLR------G 426

  Fly   344 EVVLQPEAPVHSITYCAPQTRIRA---ELLVRMVDHYKSTLAVYG----HELLPRFSSP------ 395
            ...:.|..     .|..|..|:..   .|      ::.|...|..    |.|..::|:.      
Zfish   427 GSRITPTG-----LYALPCERLECFYWGL------YFNSNTMVASKKGIHMLAQKWSNTLRELDL 480

  Fly   396 --KPFHSRIDSLMLLMCRQCFNVDTLIIRE------KVSTSTLLLIAKTAKNLQHLHV 445
              :||..  :.|.:.|.....:|.....|.      |:::|.|.|:...|..|::|::
Zfish   481 ANQPFSE--EDLEIAMGHLAHSVGVEFFRSLNLSGTKITSSALRLLINQAPALKYLNL 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 14/48 (29%)
fbxl6NP_001296447.1 F-box-like 147..195 CDD:289689 13/47 (28%)
AMN1 213..396 CDD:187754 33/196 (17%)
leucine-rich repeat 229..254 CDD:275381 2/27 (7%)
leucine-rich repeat 255..280 CDD:275381 5/31 (16%)
leucine-rich repeat 281..306 CDD:275381 7/25 (28%)
leucine-rich repeat 307..334 CDD:275381 4/26 (15%)
leucine-rich repeat 335..362 CDD:275381 2/26 (8%)
AMN1 <391..>542 CDD:187754 36/172 (21%)
leucine-rich repeat 391..418 CDD:275381 6/33 (18%)
leucine-rich repeat 419..438 CDD:275381 8/29 (28%)
leucine-rich repeat 445..473 CDD:275381 5/33 (15%)
leucine-rich repeat 475..505 CDD:275381 5/31 (16%)
leucine-rich repeat 506..530 CDD:275381 6/23 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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