DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11044 and Fbxl13

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:XP_011248071.1 Gene:Fbxl13 / 320118 MGIID:2443416 Length:889 Species:Mus musculus


Alignment Length:526 Identity:96/526 - (18%)
Similarity:169/526 - (32%) Gaps:179/526 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 LGLRRKSSAQLEVMQKAGWKIDGDEKACYIDVDEDEDQDTENMIE-SNWRY-------------- 53
            |.||.....|.:.:..|.||    |:|.:.....::|..:::.:: ..|::              
Mouse   168 LRLRHLFYMQRQRIILAKWK----ERARHKSKTREDDLISKHELQLKKWKFKLGKPISLEGSLSD 228

  Fly    54 --------------LPDLVLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLTKP 104
                          ||:..:.|||.|||.|:......|.|.|.......::||:           
Mouse   229 IAVENRRIAFDISVLPEQAILQIFLYLTFKDMMACSRVNRSWMAMIQRGSLWNS----------- 282

  Fly   105 KFNYYSGWQFCLDHMRTQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLTWNIDKGREVNPDTQF 169
                                          |:|....:..:.....|:..|.::..|     ..|
Mouse   283 ------------------------------IDFSTVKNIADKCVVTTLQKWRLNVLR-----LNF 312

  Fly   170 IGIGSRIRTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDFVLERYEA 234
            .|...|.:||.....|.                            .|.:|:......|..|  ..
Mouse   313 RGCDFRTKTLKAVSHCK----------------------------NLQELNVSDCQSFTDE--SM 347

  Fly   235 NHLLDEVVCSCCTKMRVLNLVNVT----TMHCPIMHVGLFLNLQVLTISPQNIDDDVLSLLADTK 295
            .|:.:.     |..:..|||.|.|    ||.   :....|.|||.|:::       ......|..
Mouse   348 RHISEG-----CPGVLYLNLSNTTITNRTMR---LLPRYFHNLQNLSLA-------YCRKFTDKG 397

  Fly   296 LRHLHLLQNCYTPSHLTISAC---GVKAWRNVKKTNPRLRVHLRLEN---LTDGEV-VLQPEAP- 352
            |::|:|...|:...:|.:|.|   .|:.:||:..:...: |||.:.:   |||..| ||..:.| 
Mouse   398 LQYLNLGNGCHKLIYLDLSGCTQISVQGFRNIASSCTGI-VHLTINDMPTLTDNCVKVLVEKCPR 461

  Fly   353 VHSITYC-APQ--------------TRIRAELLVRMVD--------HYKSTLAVYGHELLPRFSS 394
            :.|:... :|.              .:||.|...|:.|        :|.....:|..:......|
Mouse   462 ISSVVLIGSPHISDSAFKALSSCDLKKIRFEGNKRISDACFKSIDRNYPGINHIYMVDCKGLTDS 526

  Fly   395 PKPFHSRIDSLMLLMCRQCFNVD------------TLIIRE-------KVSTSTLLLIAKTAKNL 440
            .....|.:..|.:|....|..:.            ::.:||       .:..|:::.:::...||
Mouse   527 SLKSLSLLKQLTVLNLTNCIRIGDIGLKHFFDGPASIRLRELNLTNCSLLGDSSVIRLSERCPNL 591

  Fly   441 QHLHVR 446
            .:|::|
Mouse   592 HYLNLR 597

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 15/70 (21%)
Fbxl13XP_011248071.1 F-box-like 240..284 CDD:372399 14/84 (17%)
leucine-rich repeat 255..268 CDD:275381 4/12 (33%)
leucine-rich repeat 280..306 CDD:275381 6/66 (9%)
AMN1 306..475 CDD:187754 48/219 (22%)
leucine-rich repeat 307..330 CDD:275381 7/55 (13%)
leucine-rich repeat 331..356 CDD:275381 6/31 (19%)
leucine-rich repeat 357..381 CDD:275381 8/26 (31%)
leucine-rich repeat 382..409 CDD:275381 8/33 (24%)
leucine-rich repeat 410..435 CDD:275381 6/24 (25%)
leucine-rich repeat 436..461 CDD:275381 9/25 (36%)
leucine-rich repeat 462..484 CDD:275381 2/21 (10%)
AMN1 473..605 CDD:187754 19/125 (15%)
leucine-rich repeat 486..511 CDD:275381 6/24 (25%)
leucine-rich repeat 512..536 CDD:275381 3/23 (13%)
leucine-rich repeat 537..564 CDD:275381 3/26 (12%)
leucine-rich repeat 565..590 CDD:275381 3/24 (13%)
leucine-rich repeat 591..610 CDD:275381 3/7 (43%)
leucine-rich repeat 617..645 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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