DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11044 and Fbxl12

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001273458.1 Gene:Fbxl12 / 30843 MGIID:1354738 Length:349 Species:Mus musculus


Alignment Length:386 Identity:87/386 - (22%)
Similarity:133/386 - (34%) Gaps:147/386 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 IESNW-----------RYLPDLVLEQIFTYLTPKERYYAGL-VCRQWYRAFYLPTVWNNFLVDDR 99
            |.|:|           |.||..      |.|.|:.   .|. ||.:|.|           |||||
Mouse    20 IPSSWKKPKGSQRRGARLLPSQ------TILLPRN---PGCRVCHRWKR-----------LVDDR 64

  Fly   100 TL----------TKPKFNYYSGWQFCLDHMRTQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLT 154
            .|          .:||..    |.....:|.::....|:|.|:......|..| ..:.:.:....
Mouse    65 WLWRHVDLTLYTMRPKVM----WHLLRRYMASRLYSLRMGGYLFSGSQAPQLS-PALMRALGQKC 124

  Fly   155 WNIDK------GREVNPDTQFIGIGSRIRTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELL 213
            .|:.:      ...:.|.|   .:.|.:|||..| .|.:|                ::.:.||  
Mouse   125 PNLKRLCLHVADLSMVPIT---SLPSTLRTLELH-SCEIS----------------MIWLQKE-- 167

  Fly   214 LRLTDLHTLKLVD-FVLERYEA---NHLLDEVVCSCCTKMRVL-NLVNVTTMHCPIMHVGLFLNL 273
               .|...|.|:: .||:|..|   .||      ...|:.|.| :||...|..  :...||..:|
Mouse   168 ---QDPTVLPLLECIVLDRVPAFRDEHL------QGLTRFRALRSLVLGGTYR--VTETGLDASL 221

  Fly   274 QVLTISPQNIDDDVLSLLADTKL----RHLH------------------------LLQN-CY--- 306
            |.|:.. |.::....:|.||:.|    |||.                        :|:: |:   
Mouse   222 QELSYL-QRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVGGLSAQGLVFLEGMPVLESLCFQGP 285

  Fly   307 -------TPSHLTISACGVKAWRNVKKTNPRLRVHLRLENL----TDGEVVLQPEAPVHSI 356
                   ||:.: :|:|         .|.|:||| |.::.|    .:.|.:|....| |.|
Mouse   286 LITPDMPTPTQI-VSSC---------LTMPKLRV-LEVQGLGWEGQEAEKILCKGLP-HCI 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 12/54 (22%)
Fbxl12NP_001273458.1 F-box-like <51..73 CDD:289689 10/32 (31%)
leucine-rich repeat 127..148 CDD:275381 2/23 (9%)
AMN1 144..>249 CDD:187754 34/135 (25%)
leucine-rich repeat 149..175 CDD:275381 10/47 (21%)
leucine-rich repeat 176..200 CDD:275381 7/29 (24%)
leucine-rich repeat 201..226 CDD:275381 9/26 (35%)
leucine-rich repeat 227..252 CDD:275381 8/25 (32%)
leucine-rich repeat 253..276 CDD:275381 0/22 (0%)
leucine-rich repeat 277..306 CDD:275381 7/38 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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