DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11044 and Amn1

DIOPT Version :9

Sequence 1:	NP_611456.1	Gene:	CG11044 / 37281	FlyBaseID:	FBgn0034484	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001008334.2	Gene:	Amn1 / 302032	RGDID:	1308119	Length:	258	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	68/292 - (23%)
Similarity:	106/292 - (36%)	Gaps:	94/292 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 QFCLS----RIGRYVRGIEFRPWHSFNNIFQFMTMLTWNIDKGR-------EV-NPDTQFIGIGS 174
            :.||.    .|.||:..|::.|.:..:.:.:.|:|      :||       || :|:.|.:.:.|
  Rat    12 ELCLRCLIINISRYISDIKYLPPNIKDRLIKIMSM------RGRITDSNINEVLHPEVQRLDLRS 70

  Fly   175 RIRTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDFVLERYEANHLLD 239
                      ||:|.                     ..|..|.....||.::....|...|.:..
  Rat    71 ----------CNISD---------------------VALQHLCKCRKLKALNLKSCREHRNSITS 104

  Fly   240 E---VVCSCCTKMRVLNLVNVTTMHCPIMHVG---LFLNLQVLTI----SPQNIDDDVLSLLADT 294
            |   .|.|.|:.:..::|...    |.:...|   |.||.|:|.|    ...:|.|:.|..|.
  Rat   105 EGIKAVASSCSDLHEISLKGC----CSVTDEGVLALALNCQLLKIIDLGGCLSITDESLHALG-- 163

  Fly   295 KLRHLHLLQNCYTPSHLTISACGVKAW------RNVKKTNPRLRVHLRLENLTDGEVVLQPEAPV 353
              ::...|| |...|...:|..||.|.      :.:::.|....:     ||||..|    ||
  Rat   164 --KNCPFLQ-CVDFSTTQVSDNGVVALVSGPCAKQLEEINMGYCI-----NLTDKAV----EA-- 214

  Fly   354 HSITYCAPQTRIRAELLVR----MVDHYKSTL 381
             ::|.| ||..|   ||..    :.||.:..|
  Rat   215 -ALTAC-PQICI---LLFHGCPLITDHSREVL 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689
Amn1	NP_001008334.2	leucine-rich repeat	10..35	CDD:275381	7/22 (32%)
		leucine-rich repeat	36..58	CDD:275381	4/27 (15%)
		AMN1	37..257	CDD:187754	61/267 (23%)
		leucine-rich repeat	63..86	CDD:275381	7/53 (13%)
		leucine-rich repeat	87..116	CDD:275381	8/28 (29%)
		leucine-rich repeat	117..142	CDD:275381	6/28 (21%)
		leucine-rich repeat	143..168	CDD:275381	6/28 (21%)
		leucine-rich repeat	169..195	CDD:275381	8/26 (31%)
		leucine-rich repeat	196..221	CDD:275381	10/37 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900