DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11044 and FBXL4

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001265645.1 Gene:FBXL4 / 26235 HGNCID:13601 Length:621 Species:Homo sapiens


Alignment Length:315 Identity:63/315 - (20%)
Similarity:100/315 - (31%) Gaps:136/315 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly   223 KLVDFVLERYEANHLLDEVVCSCCTKMRVLNLVNVTTMHC--PIMHVGLFLNLQVLTISPQNIDD 285
            :|:..:|     |||....:|      |:.....:.:.||  |:.::  .||||           
Human   286 ELIQLIL-----NHLTLPDLC------RLAQTCKLLSQHCCDPLQYI--HLNLQ----------- 326

  Fly   286 DVLSLLADTKLRHLHLLQNCYTPSHLTISACGVKAWRNVKKTNPR-----------LRV----HL 335
            ...:.|.||.|..|.             |.|.:..|.|:..|..|           |:|    .:
Human   327 PYWAKLDDTSLEFLQ-------------SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELV 378

  Fly   336 RLE-------NLTDGEVVLQ--PEAPVHSITYCAPQTRIRAELLVRMVDHYKSTLAVYGHELLPR 391
            |||       |.|..||:.:  |.....:::.|                           :.|| 
Human   379 RLELSCSHFLNETCLEVISEMCPNLQALNLSSC---------------------------DKLP- 415

  Fly   392 FSSPKPFH--SRIDSLMLLMCRQCFNVDTLIIREKVSTSTLLLIAKTAKNLQHLHVRRFAVILRC 454
               |:.|:  :::.||..|          ::.|.||..:.||.|......||||.:....:|   
Human   416 ---PQAFNHIAKLCSLKRL----------VLYRTKVEQTALLSILNFCSELQHLSLGSCVMI--- 464

  Fly   455 DWPRHPEWSNEFYAWLKRNSRSYEAVEREISQILGYKWRLLSDRDF---KQLTVN 506
                                ..|:.    |:.::|.|.:.|...|.   |.:|.|
Human   465 --------------------EDYDV----IASMIGAKCKKLRTLDLWRCKNITEN 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689
FBXL4NP_001265645.1 F-box-like 280..318 CDD:315592 9/42 (21%)
leucine-rich repeat 295..317 CDD:275381 5/27 (19%)
leucine-rich repeat 318..346 CDD:275381 11/53 (21%)
leucine-rich repeat 347..376 CDD:275381 6/28 (21%)
LRR 1 376..397 7/20 (35%)
leucine-rich repeat 377..398 CDD:275381 7/20 (35%)
AMN1 394..601 CDD:332986 31/170 (18%)
LRR 2 402..421 5/49 (10%)
leucine-rich repeat 403..427 CDD:275381 5/54 (9%)
LRR 3 427..448 9/30 (30%)
leucine-rich repeat 428..452 CDD:275381 8/33 (24%)
LRR 4 452..474 7/48 (15%)
leucine-rich repeat 453..480 CDD:275381 9/53 (17%)
LRR 5 480..501 5/16 (31%)
leucine-rich repeat 481..506 CDD:275381 5/15 (33%)
LRR 6 504..524
leucine-rich repeat 507..534 CDD:275381
LRR 7 532..558
leucine-rich repeat 535..560 CDD:275381
LRR 8 559..583
leucine-rich repeat 561..586 CDD:275381
LRR 9 584..609
leucine-rich repeat 587..612 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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