DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11044 and Fbxl16

DIOPT Version :9

Sequence 1:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001366323.1 Gene:Fbxl16 / 214931 MGIID:2448488 Length:575 Species:Mus musculus


Alignment Length:433 Identity:89/433 - (20%)
Similarity:138/433 - (31%) Gaps:161/433 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 VLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLT-----KPKFNYYSGWQ---- 113
            :|..:|.|.:..|:.....||:.|.|..|.|..|..       ||     |..:|...|.:    
Mouse   197 ILNGLFWYFSACEKCILAQVCKAWRRVLYQPKFWAG-------LTPVLHAKELYNVLPGGEKEFV 254

  Fly   114 ------------FCLDHMR--------TQFCLSRIGRYVRGIEFRPWHSFNNIFQFMTMLTWNID 158
                        |||..:.        ..:.||:.|  |:.:..:           .:.:|   |
Mouse   255 NLQGFAARGFEGFCLVGVSDLDICEFIDNYSLSKKG--VKAMSLK-----------RSTIT---D 303

  Fly   159 KGREV----------------NPDTQ---FIGIGSRIRTLVYHFPCNMSQPNDPEGIKLFGTGGQ 204
            .|.||                |..|:   :..:.:||.:|......|::.    :.|...   .|
Mouse   304 AGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVAD----DAIAAI---SQ 361

  Fly   205 LLRVLKELLLRLTDLHTLKLVDFVLERYEANHLLDEVVCSCCTKMRVLNLVNVTTMHCPIMHVGL 269
            ||..|.||.|:...:....|..|...:..:.|.|..:.|...|...|:|:|:...          
Mouse   362 LLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLP---------- 416

  Fly   270 FLNLQVLTISP-QNIDDDVLSLLADT--KLRHLHLLQNC--YTPSHLTISACGVKAWRNVKKTNP 329
              ||..|::|. ..:.||.:.|:|:.  |||.|. |..|  .|...|...||.:.          
Mouse   417 --NLTSLSLSGCSKVTDDGVELVAENLRKLRSLD-LSWCPRITDMALEYVACDLH---------- 468

  Fly   330 RLRVHLRLENLTDGEVVLQPEAPVHSITYCAPQTRIRAELLVRMVD---HYKSTLAVYGHELLPR 391
                  |||     |:||                    :..||:.|   .|.||::         
Mouse   469 ------RLE-----ELVL--------------------DRCVRITDTGLSYLSTMS--------- 493

  Fly   392 FSSPKPFHSRIDSLMLLMCRQCFNVDTLIIREKVSTSTLLLIA 434
                        ||..|..|.|..|....::..::...|.|::
Mouse   494 ------------SLRSLYLRWCCQVQDFGLKHLLAMRNLRLLS 524

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 11/35 (31%)
Fbxl16NP_001366323.1 PHA03247 <31..193 CDD:223021
AMN1 297..509 CDD:187754 64/307 (21%)
leucine-rich repeat 316..339 CDD:275381 2/22 (9%)
leucine-rich repeat 340..365 CDD:275381 7/31 (23%)
leucine-rich repeat 366..391 CDD:275381 6/24 (25%)
leucine-rich repeat 392..417 CDD:275381 7/36 (19%)
leucine-rich repeat 418..443 CDD:275381 7/24 (29%)
leucine-rich repeat 444..469 CDD:275381 9/41 (22%)
leucine-rich repeat 470..494 CDD:275381 11/69 (16%)
leucine-rich repeat 495..514 CDD:275381 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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