DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11044 and B0564.6

DIOPT Version :9

Sequence 1:	NP_611456.1	Gene:	CG11044 / 37281	FlyBaseID:	FBgn0034484	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_502527.1	Gene:	B0564.6 / 182046	WormBaseID:	WBGene00007206	Length:	423	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	65/356 - (18%)
Similarity:	120/356 - (33%)	Gaps:	126/356 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LPDLVLEQIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLTKPKFNYYSGWQFCLDH 118
            |||.:.|...|        .:.:.|.:|..|..:...:...|...|     |..|:.....||
Worm   127 LPDSIEEISIT--------NSMIECSEWDVATIIRKSFGTLLKKCR-----KLRYFEISGQCL-- 176

  Fly   119 MRTQF-----CLSRIGRYVRGIEFRPWHSFN-NIFQFMTMLTWNIDKG-REVNPDTQFIGIGSRI 176
            |.:.|     .|..|...|..:.....||.. |...|:.      ||. :.:|....||.
Worm   177 MNSHFHVDPKILQFISNTVEHLAIAVGHSLTINSLAFLK------DKRLKTLNLQRSFIS----- 230

  Fly   177 RTLVYHFPCNMSQPNDPEGIKLFGTGGQLLRVLKELLLRLTDLHTLKLVDF--VLERYEANHL-- 237
                   ||::..                :..:.:.:..|....::.|:|.  :.|.....||
Worm   231 -------PCDLEH----------------IVAMADTITHLDLSRSVNLLDCRQIAELVNLRHLSL 272

  Fly   238 ---------------------LDEVVCSCCTKMRVLNLVNVTTMHCPIMHVGLFLNLQVLTI-SP 280
                                 |:|:...||..:.|.:|:.:..::          ||:.|:: ..
Worm   273 KNNKEGVRDDSLQLIIKNCSKLEELSLDCCEYLTVNSLITLGNLN----------NLKQLSLPGI 327

  Fly   281 QNIDDDV-LSLLADTKLRHLHL-------------LQNCYTP-SHLTISACGVKAWRNVKKTNPR 330
            .|:||.| |.:...:||.:|::             |.:|.|. .||.:  .|::|:     ::..
Worm   328 VNVDDSVCLQISRCSKLTYLNINFCRRVQKRGLLCLLSCLTSLDHLEV--LGIRAY-----SHHL 385

  Fly   331 LRVHLR---------LENLTDGEVVLQPEAP 352
            |.:|:.         :|:::   :::.|..|
Worm   386 LALHINFPKTIVSDYVESIS---IIIPPIPP 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11044	NP_611456.1	F-box-like	51..94	CDD:289689	8/39 (21%)
B0564.6	NP_502527.1	leucine-rich repeat	106..130	CDD:275381	2/2 (100%)
		leucine-rich repeat	131..159	CDD:275381	5/35 (14%)
		leucine-rich repeat	166..193	CDD:275381	7/28 (25%)
		leucine-rich repeat	195..214	CDD:275381	4/18 (22%)
		leucine-rich repeat	219..243	CDD:275381	5/51 (10%)
		leucine-rich repeat	244..266	CDD:275381	4/21 (19%)
		leucine-rich repeat	267..293	CDD:275381	2/25 (8%)
		leucine-rich repeat	294..318	CDD:275381	6/33 (18%)
		leucine-rich repeat	319..343	CDD:275381	7/23 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900