Protein Alignment JUP and Uck

DIOPT Version :10

• Sequence 1: XP_047291890.1
• Gene: JUP / 3728
• HGNCID: 6207
• Length: 762
• Species: Homo sapiens
• Sequence 2: NP_001138105.1
• Gene: Uck / 42894
• FlyBaseID: FBgn0263398
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 199
• Identity: 36/199 - (18%)
• Similarity: 66/199 - (33%)
• Gaps: 69/199 - (34%)

Human   537 EAAVIPRLVQLLVKAHQD-AQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRL 600
            ::.|..::::.|.:|..| .||.|.:.:|..:...:...|..:...|..:....|..|.
  Fly    40 KSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNE------ 98

Human   601 NTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASA------------------PL 647
                   :|:||:::||.:   |...|:.......:::|.|....                  .:
  Fly    99 -------ELMYSTLQNILK---GHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKI 153

Human   648 MELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYGD 712
            .||.|.:           || :..|.:....:||..:                     ||| .|.
  Fly   154 RELFHMK-----------LF-VDTDSDTRLARRVPRD---------------------INE-RGR 184

Human   713 DMDA 716
            |:||
  Fly   185 DLDA 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JUP	XP_047291890.1	CTNNAbd_CTNNG	90..159	CDD:439242
		armadillo repeat	161..186	CDD:293788
		armadillo repeat	203..229	CDD:293788
		armadillo repeat	238..270	CDD:293788
		Arm	238..270	CDD:425727
		armadillo repeat	278..314	CDD:293788
		armadillo repeat	322..355	CDD:293788
		PLN03200	<345..>675	CDD:215629	27/156 (17%)
		ARM	358..398	CDD:214547
		armadillo repeat	362..397	CDD:293788
		armadillo repeat	410..435	CDD:293788
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	487..525	CDD:293788
		armadillo repeat	532..589	CDD:293788	10/52 (19%)
		armadillo repeat	594..628	CDD:293788	6/33 (18%)
		armadillo repeat	635..669	CDD:293788	7/51 (14%)
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	36/199 (18%)