Protein Alignment 18w and CG5810

DIOPT Version :10

• Sequence 1: NP_476814.1
• Gene: 18w / 37277
• FlyBaseID: FBgn0287775
• Length: 1385
• Species: Drosophila melanogaster
• Sequence 2: NP_650952.2
• Gene: CG5810 / 42513
• FlyBaseID: FBgn0038866
• Length: 428
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 124/577 - (21%)
• Similarity: 197/577 - (34%)
• Gaps: 194/577 - (33%)

  Fly     7 IITIIAVAACLLLLVADAHAQQQCNWQYGLTTMDIRCSVRALESGTGTPLDLQVAEAAGRLDLQC 71
            :|.:||.|.|          :.|...:..:.::|.|       ..|.|.|....|.|........
  Fly    11 LIAVIAFATC----------ESQKLEEIAIDSLDCR-------ENTCTNLKYPSASAVAYFSENV 58

  Fly    72 SQEL-------LHASELA---PGLFRQLQKLSELRIDACKLQRVPPNAFEGLMSLKRLTLESHNA 126
            ::.|       ||:|:||   ..:|..|.:|.|..:..|:||::....|:|..:||||.
  Fly    59 TKHLRKYETLVLHSSDLANLPRKIFLNLPQLVEFHVLECELQQIESVCFDGAKNLKRLN------ 117

  Fly   127 VWGPGKTLELHGQSFQGLKELSELHLGDNNIRQLPEGVWCSMPSLQLLNLTQNRIRSAEFLGFSE 191
             :|......|...:|:...:|.||:|.||.:..||..::..:.:||.:||:.||
  Fly   118 -FGGNALRVLDSNTFELATQLEELNLSDNQLEDLPTTIFRPLKNLQKINLSNNR----------- 170

  Fly   192 KLCAGSALSNANGAVSGGSELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALA 256
                                                                   :.||:.:..:
  Fly   171 -------------------------------------------------------LITLSQHIFS 180

  Fly   257 GLSSLRVLNISYNHLVSLPSEAFAG-NKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGN-QL 319
            .|.||:.:|:..|.||.||.|.|.. .|.|.|...|.|.|..:|..:...::.   |.||.| ||
  Fly   181 QLGSLKSINVDSNQLVELPGELFRDQRKHLSEFSAQSNQLVRIPFNIFREIDH---LSLSFNPQL 242

  Fly   320 TSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLH 384
            ...|:                         |....|      |:..|..:..:|
  Fly   243 RRLHL-------------------------SAKINE------LEATNCDLESVE----------- 265

  Fly   385 TLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQ 449
                       ||.|:..     .:|..|..|..:..||.    .||:.|.|::..|..: :.:.
  Fly   266 -----------LDGRVIG-----VQLEANPKLHELKISQP----QDLEHLYLANTNLYRL-DFLS 309

  Fly   450 DLSMLKTLDLGENQISEFKNNTFRNLNQLT---GLRLIDNRIGNITVGMFQDLPRLSVLNLAKNR 511
            ..|.|..||     :::..|  ..:|.::|   ||..:.....|:|......||.|..||..:.
  Fly   310 KASKLVDLD-----VTDIVN--LADLPKITSAKGLERLSFTYDNLTSNHMDMLPHLKDLNYLEI- 366

  Fly   512 IQSIERGAFDKNTEIEAIRLDKNFL---TDIN-GIFATLASLLWL----NLSENHLV 560
                   :.:|..||....||::|.   .::| |..|.|...:.|    .:.|:.||
  Fly   367 -------SHEKGKEIFIKDLDEDFFVEEAELNCGQLADLLEFVELPKDTTILEDRLV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
18w	NP_476814.1	leucine-rich repeat	66..91	CDD:275380	8/34 (24%)
		leucine-rich repeat	92..115	CDD:275380	7/22 (32%)
		LRR_8	115..181	CDD:404697	20/65 (31%)
		leucine-rich repeat	116..146	CDD:275380	7/29 (24%)
		leucine-rich repeat	147..170	CDD:275380	8/22 (36%)
		leucine-rich repeat	171..201	CDD:275380	6/29 (21%)
		LRR	210..592	CDD:443914	75/364 (21%)
		leucine-rich repeat	212..236	CDD:275380	0/23 (0%)
		leucine-rich repeat	237..260	CDD:275380	3/22 (14%)
		leucine-rich repeat	261..284	CDD:275380	9/23 (39%)
		leucine-rich repeat	285..308	CDD:275380	6/22 (27%)
		leucine-rich repeat	309..334	CDD:275380	7/25 (28%)
		leucine-rich repeat	335..358	CDD:275380	2/22 (9%)
		leucine-rich repeat	359..382	CDD:275380	3/22 (14%)
		leucine-rich repeat	383..406	CDD:275380	3/22 (14%)
		leucine-rich repeat	407..430	CDD:275380	5/22 (23%)
		leucine-rich repeat	431..451	CDD:275380	4/19 (21%)
		leucine-rich repeat	454..477	CDD:275380	5/22 (23%)
		leucine-rich repeat	478..499	CDD:275380	5/23 (22%)
		leucine-rich repeat	502..525	CDD:275380	4/22 (18%)
		leucine-rich repeat	526..548	CDD:275380	8/25 (32%)
		leucine-rich repeat	590..617	CDD:275380
		leucine-rich repeat	618..641	CDD:275380
		leucine-rich repeat	642..689	CDD:275380
		LRRCT	679..736	CDD:214507
		LRR	<775..>920	CDD:443914
		leucine-rich repeat	775..796	CDD:275380
		leucine-rich repeat	797..817	CDD:275380
		leucine-rich repeat	818..841	CDD:275380
		leucine-rich repeat	842..865	CDD:275380
		leucine-rich repeat	866..889	CDD:275380
		leucine-rich repeat	890..911	CDD:275380
		TIR	1045..1183	CDD:214587
CG5810	NP_650952.2	LRR	<61..353	CDD:443914	92/437 (21%)
		leucine-rich repeat	65..88	CDD:275380	7/22 (32%)
		leucine-rich repeat	89..112	CDD:275380	7/22 (32%)
		leucine-rich repeat	113..136	CDD:275380	7/29 (24%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..184	CDD:275380	9/88 (10%)
		leucine-rich repeat	185..209	CDD:275380	9/23 (39%)
		leucine-rich repeat	210..231	CDD:275380	6/20 (30%)