Protein Alignment 18w and CG32055

DIOPT Version :10

• Sequence 1: NP_476814.1
• Gene: 18w / 37277
• FlyBaseID: FBgn0287775
• Length: 1385
• Species: Drosophila melanogaster
• Sequence 2: NP_729599.1
• Gene: CG32055 / 39188
• FlyBaseID: FBgn0052055
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 145/571 - (25%)
• Similarity: 242/571 - (42%)
• Gaps: 76/571 - (13%)

  Fly    68 DLQCSQELLHASELAPGLFRQLQKLSELRIDACKLQRVPPNAFEGLMSLKRLTLESHNAVWGPGK 132
            |||..::|.:.|.|.    |:::...:|            |.:.|             ..|...|
  Fly    19 DLQECEDLGNGSYLC----REIESFEQL------------NRYVG-------------KNWKSVK 54

  Fly   133 TLELH--------GQSFQGLKELSELHLGDNNIRQLPEGVWCSMPSLQLLNLTQ---NRIRSAEF 186
            .:..|        |: ..||..|.:|.|.::....|.|.......:||.||||.   :.::|.:|
  Fly    55 VVNEHTGIERAEDGE-LPGLSTLLQLDLSESGGVTLGEKGLQDFKALQKLNLTHAQLDELKSEQF 118

  Fly   187 LGFSEKLCAGSALSNANGAVSGGSELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLA 251
                                ...||:...|||:|::.::.... .|....|...:...|.|:.:.
  Fly   119 --------------------PNPSEMINFDVSYNDILAITTKL-MSGFGNLVYANFSENLIAVIE 162

  Fly   252 PNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSG 316
            |||...:.:||.|:::.|:..::   ....|..||.|.:..|:|.:.....|..|.:|..|.|..
  Fly   163 PNAFRHMKNLRFLDLTTNYQENI---TLGENANLRFLSISNNNLRDFQWCHLRVLPKLEELHLHS 224

  Fly   317 NQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFK---ELYFLQILDMRNNSIGHIEEGAFL 378
            |.|  .|:|...|..|..|.|||:|||.|..|....|.   |:..|::||..:|.:..:::..|.
  Fly   225 NWL--EHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFC 287

  Fly   379 PLYNLHTLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTE 443
            .|..|.||||..|:::.:..|.|.||..|..|.|..|.:||:....|.|.:.|::||||.|.:.:
  Fly   288 RLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQK 352

  Fly   444 VPEAV---QDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVL 505
            :...|   :.|..|..|||..|.|::.......::..:..|||..||:.::.:.||..|.:|.:|
  Fly   353 LGLRVFGERILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAPLRQLQLL 417

  Fly   506 NLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFATLASLLWLNLSENHLVWFDYAFIPSN 570
            .:.:||::.|:....|....:..:.|:.|.||.:..:.::...|...|::.....| ....:...
  Fly   418 TINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLEGNPW-QCLCLDEI 481

  Fly   571 LKWLD-IHGNYIEALGNYYKLQEEIRVTT-LDASHNRITEIGAMSVPNSIE 619
            ..||: .|.:|......|:..::.:.|.| :|.....:.|..|..:..|.|
  Fly   482 TSWLNGRHVSYARPSSAYFSGRKPLCVVTPMDKCLRDLQETKAQGIVESYE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
18w	NP_476814.1	leucine-rich repeat	66..91	CDD:275380	7/22 (32%)
		leucine-rich repeat	92..115	CDD:275380	3/22 (14%)
		LRR_8	115..181	CDD:404697	17/76 (22%)
		leucine-rich repeat	116..146	CDD:275380	6/37 (16%)
		leucine-rich repeat	147..170	CDD:275380	5/22 (23%)
		leucine-rich repeat	171..201	CDD:275380	8/32 (25%)
		LRR	210..592	CDD:443914	109/388 (28%)
		leucine-rich repeat	212..236	CDD:275380	5/23 (22%)
		leucine-rich repeat	237..260	CDD:275380	6/22 (27%)
		leucine-rich repeat	261..284	CDD:275380	5/22 (23%)
		leucine-rich repeat	285..308	CDD:275380	7/22 (32%)
		leucine-rich repeat	309..334	CDD:275380	9/24 (38%)
		leucine-rich repeat	335..358	CDD:275380	11/25 (44%)
		leucine-rich repeat	359..382	CDD:275380	6/22 (27%)
		leucine-rich repeat	383..406	CDD:275380	10/22 (45%)
		leucine-rich repeat	407..430	CDD:275380	8/22 (36%)
		leucine-rich repeat	431..451	CDD:275380	7/22 (32%)
		leucine-rich repeat	454..477	CDD:275380	6/22 (27%)
		leucine-rich repeat	478..499	CDD:275380	7/20 (35%)
		leucine-rich repeat	502..525	CDD:275380	6/22 (27%)
		leucine-rich repeat	526..548	CDD:275380	4/21 (19%)
		leucine-rich repeat	590..617	CDD:275380	5/27 (19%)
		leucine-rich repeat	618..641	CDD:275380	1/2 (50%)
		leucine-rich repeat	642..689	CDD:275380
		LRRCT	679..736	CDD:214507
		LRR	<775..>920	CDD:443914
		leucine-rich repeat	775..796	CDD:275380
		leucine-rich repeat	797..817	CDD:275380
		leucine-rich repeat	818..841	CDD:275380
		leucine-rich repeat	842..865	CDD:275380
		leucine-rich repeat	866..889	CDD:275380
		leucine-rich repeat	890..911	CDD:275380
		TIR	1045..1183	CDD:214587
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	5/22 (23%)
		leucine-rich repeat	100..123	CDD:275380	8/42 (19%)
		LRR_8	126..180	CDD:404697	14/54 (26%)
		leucine-rich repeat	128..147	CDD:275380	5/19 (26%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		LRR	171..>486	CDD:443914	92/320 (29%)
		leucine-rich repeat	172..192	CDD:275380	5/22 (23%)
		leucine-rich repeat	193..216	CDD:275380	7/22 (32%)
		leucine-rich repeat	217..240	CDD:275380	9/24 (38%)
		leucine-rich repeat	241..267	CDD:275380	11/25 (44%)
		leucine-rich repeat	268..291	CDD:275380	6/22 (27%)
		leucine-rich repeat	292..315	CDD:275380	10/22 (45%)
		leucine-rich repeat	316..339	CDD:275380	8/22 (36%)
		leucine-rich repeat	340..365	CDD:275380	8/24 (33%)
		leucine-rich repeat	366..389	CDD:275380	6/22 (27%)
		leucine-rich repeat	390..413	CDD:275380	8/22 (36%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)