Protein Alignment 18w and CG5819

DIOPT Version :10

• Sequence 1: NP_476814.1
• Gene: 18w / 37277
• FlyBaseID: FBgn0287775
• Length: 1385
• Species: Drosophila melanogaster
• Sequence 2: NP_611660.1
• Gene: CG5819 / 37547
• FlyBaseID: FBgn0034717
• Length: 915
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 137/555 - (24%)
• Similarity: 216/555 - (38%)
• Gaps: 148/555 - (26%)

  Fly   209 GSELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVS 273
            |..::.||:|.|:....|..:  :.:..|..|.|..|.||::....|.|.:|||.|.::.|.:.|
  Fly    53 GIPVEHLDLSGNKFLEFPTLY--ADIDSLIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNSIDS 115

  Fly   274 ----LPSEAFAGNKELRELHLQGNDLYELPKGLLHRL---EQLLVLDLS--------GNQLTSHH 323
                .|:|||.....|:.|.|.||.|.....|....|   ..|..|.||        |:|:.:.
  Fly   116 WESLSPNEAFKYAPSLKRLGLDGNRLGSFGNGESFELLTSSSLTDLGLSSCGISSIGGDQMVNQ- 179

  Fly   324 VDNSTFAGLIRLIVLNLSNNALTRIG---SKTFKELYFLQILDMRNNSIGHIEEGAFL-PLYNLH 384
                    |..|..|||:||.|.:|.   |:|      |::||:.|.||.:: .|.|| .:.||.
  Fly   180 --------LPNLERLNLANNQLAQIAALPSRT------LRVLDLSNCSIKNL-SGFFLDAMQNLE 229

  Fly   385 TLNLAEN-------------------RLH----TLDNRIFNGLYVLTKLTLNNNLVSIVESQAFR 426
            .|||:.|                   :|.    .||:...:||..||::.|..||:.:|:...|.
  Fly   230 ALNLSRNTELQFDSLSEDPILTYMLRKLDVSYCNLDSIELSGLPQLTEVRLQGNLLRVVDVNTFA 294

  Fly   427 NCSDLKELDLSSNQLTEV-PEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGN 490
            |.|.|:.:|||.|.|..: .:|...|..||.|:|..|:|:....|..||.:.|..|.|..|.:..
  Fly   295 NNSMLEVVDLSQNVLRHIGQDAFAKLKRLKELNLAFNEIARLDRNFIRNNDVLVELNLSRNVLQK 359

  Fly   491 ITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFATLASLLWLNLS 555
            :|             .:..|.:::|
  Fly   360 LT-------------KIVSNSVRTI---------------------------------------- 371

  Fly   556 ENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITEIGAMSVPNSIEL 620
                          |:.|.:|......||.:...:|:      ||.|:|.||::.......:::.
  Fly   372 --------------NMSWCEITSIESTALSSLSVIQK------LDLSNNLITDMPTFMRSETLQQ 416

  Fly   621 LFINNNIIGQIQANTFVDKTRLARVDLYANVLSKISLNALRVAPV-----SAEKPVPEFYLGGNP 680
            |.:.|..:..::.|||.:...||.:.|..|.|:         :|:     ...|.:.:.:||.||
  Fly   417 LNLANCRLTTVRNNTFREFPELADLHLNGNRLT---------SPIPPNYFDGNKFLDQLWLGDNP 472

  Fly   681 FECDCSMEWLQRINNLTTRQHPHVVDLGNIECLMP 715
            :.|||.........:..|.:...:.|..::.|..|
  Fly   473 WICDCHSPLFVDFYDYLTAKPAKIKDRNHLRCAAP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
18w	NP_476814.1	leucine-rich repeat	66..91	CDD:275380
		leucine-rich repeat	92..115	CDD:275380
		LRR_8	115..181	CDD:404697
		leucine-rich repeat	116..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..201	CDD:275380
		LRR	210..592	CDD:443914	106/424 (25%)
		leucine-rich repeat	212..236	CDD:275380	5/23 (22%)
		leucine-rich repeat	237..260	CDD:275380	8/22 (36%)
		leucine-rich repeat	261..284	CDD:275380	9/26 (35%)
		leucine-rich repeat	285..308	CDD:275380	8/25 (32%)
		leucine-rich repeat	309..334	CDD:275380	7/32 (22%)
		leucine-rich repeat	335..358	CDD:275380	10/25 (40%)
		leucine-rich repeat	359..382	CDD:275380	9/23 (39%)
		leucine-rich repeat	383..406	CDD:275380	10/45 (22%)
		leucine-rich repeat	407..430	CDD:275380	8/22 (36%)
		leucine-rich repeat	431..451	CDD:275380	7/20 (35%)
		leucine-rich repeat	454..477	CDD:275380	9/22 (41%)
		leucine-rich repeat	478..499	CDD:275380	5/20 (25%)
		leucine-rich repeat	502..525	CDD:275380	2/22 (9%)
		leucine-rich repeat	526..548	CDD:275380	0/21 (0%)
		leucine-rich repeat	590..617	CDD:275380	7/26 (27%)
		leucine-rich repeat	618..641	CDD:275380	5/22 (23%)
		leucine-rich repeat	642..689	CDD:275380	14/51 (27%)
		LRRCT	679..736	CDD:214507	9/37 (24%)
		LRR	<775..>920	CDD:443914
		leucine-rich repeat	775..796	CDD:275380
		leucine-rich repeat	797..817	CDD:275380
		leucine-rich repeat	818..841	CDD:275380
		leucine-rich repeat	842..865	CDD:275380
		leucine-rich repeat	866..889	CDD:275380
		leucine-rich repeat	890..911	CDD:275380
		TIR	1045..1183	CDD:214587
CG5819	NP_611660.1	RNA1	<56..193	CDD:444072	44/147 (30%)
		leucine-rich repeat	56..78	CDD:275380	5/23 (22%)
		leucine-rich repeat	79..102	CDD:275380	8/22 (36%)
		leucine-rich repeat	103..130	CDD:275380	9/26 (35%)
		leucine-rich repeat	131..155	CDD:275380	8/23 (35%)
		LRR	134..>466	CDD:443914	101/429 (24%)
		leucine-rich repeat	158..182	CDD:275380	7/32 (22%)
		leucine-rich repeat	204..227	CDD:275380	9/23 (39%)
		leucine-rich repeat	254..274	CDD:275380	5/19 (26%)
		leucine-rich repeat	275..298	CDD:275380	8/22 (36%)
		leucine-rich repeat	299..322	CDD:275380	8/22 (36%)
		leucine-rich repeat	323..346	CDD:275380	9/22 (41%)
		leucine-rich repeat	347..391	CDD:275380	12/110 (11%)
		leucine-rich repeat	392..413	CDD:275380	7/26 (27%)
		leucine-rich repeat	414..437	CDD:275380	5/22 (23%)
		LRRCT	471..517	CDD:214507	9/37 (24%)