Protein Alignment 18w and Tehao

DIOPT Version :10

• Sequence 1: NP_476814.1
• Gene: 18w / 37277
• FlyBaseID: FBgn0287775
• Length: 1385
• Species: Drosophila melanogaster
• Sequence 2: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Alignment Length: 884
• Identity: 206/884 - (23%)
• Similarity: 343/884 - (38%)
• Gaps: 255/884 - (28%)

  Fly   342 NNALTRIGSKTFKELYF----LQIL---DMRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLDNR 399
            ::.|..:|.:|.|.:.|    |:.:   |:.|:..|::|......:...|
  Fly   106 SDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWH--------------- 155

  Fly   400 IFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQDL--SMLKTLDLGEN 462
             |..:..|.|....:::..:.|| .|.....|::|.||.| :|.:|..:...  ..||||.:...
  Fly   156 -FGSVPGLKKFKFFSHVPELQES-IFHGFDTLRDLHLSVN-VTTLPGNMLSTVNGTLKTLTIESP 217

  Fly   463 QISEFKNNTFRNLNQLTGLRL-----IDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDK 522
            .|..|.|...|.|.||..|.|     ...|...:....|..:..|..:.|| :...|:.|..|..
  Fly   218 GIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLA-SATSSVNRSMFKG 281

  Fly   523 NTEIEAIRLDKN-FLTDING-IFATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALG 585
            ..:::.|:::.| .|.::.| ||....:|..|:||.|.:|              .:|.:..:.||
  Fly   282 TNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIV--------------TLHEDVFKGLG 332

  Fly   586 NYYKLQEEIRVTTLDASHNRITEIGA-MSVP-NSIELLFINNNIIGQIQANTFVDKTRLARVDLY 648
            |         :|.||.|.||:|.:.: :..| .|:.:|.:|.|.:..:..:.|.|
  Fly   333 N---------LTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQD---------- 378

  Fly   649 ANVLSKISLNALRVAPVSAEKPVPEFYLGGNPFECDCSMEWLQRINNLTTRQHPHVVDLGNIECL 713
                 .:|||.:.:...       :||
  Fly   379 -----VVSLNYIEMVNT-------QFY-------------------------------------- 393

  Fly   714 MPHSRSAPLRPLASLSASDFVCKYESHCPPTCHCCEYEQCECEVICPGNCSCFHDATWATNIVDC 778
                            .:..:..||:........|:|:..|.:  |...|.|:...:..:.||||
  Fly   394 ----------------GATLLMNYEAVVCTNDEACQYKSAEWQ--CDPRCICWVQRSVGSLIVDC 440

  Fly   779 GRQDLAALPNRIPQD--VSDLYLDGNN----MPELEVGHLTGRRNLRALYLNASNLMTLQNGSLA 837
            ....|..||: :|:.  :|.:...|||    :|  .|...:|..|:..|:|:.:||.:|.:|.
  Fly   441 RGTSLEELPD-LPRTTLLSTVLKVGNNSLTSLP--TVSEHSGYANVSGLFLSDNNLTSLGSGD-- 500

  Fly   838 QLV-NLRVLHLENNKLTALEGTEFRSLGLLRELYLHNNMLTHISNATFEPLVSLEVLRLDNNRLS 901
            ||. ||..|.:..|::.:| ..||  |..|:|   .||.:|
  Fly   501 QLPDNLTHLDVRGNQIQSL-SDEF--LLFLQE---PNNTMT------------------------ 535

  Fly   902 SLPHLQYRHSLQGLTLGRNAWSCRCQQLRELAQFVSDNAMVVRDAHDIYCLDAGIKRELELIGNL 966
                         |:|..|..:|.|:.| .|..||..|...|||..||.|...  |:..:.:
  Fly   536 -------------LSLSGNPITCGCESL-SLLFFVRTNPQRVRDIADIVCTKQ--KKSFQQM--- 581

  Fly   967 ANGPDCSDLLDASASNISSSQDLAGGYRLPLLAAVLVLIFLVVVLIIVF--VFRESVRMWLFAHY 1029
                              .:.:|...|.| |::.|:..:.:|:.|:.||  :|::.:::||   |
  Fly   582 ------------------EAFELCPSYVL-LISCVVGGLVIVICLLTVFYLMFQQELKIWL---Y 624

  Fly  1030 GVRVC-----EPRFEDAGKLYDAIILHSEKDYEFVCRNIAAELEHGRPPFRLCIQQRD------L 1083
            ...:|     |... |..|.|||.|.:|.||.|.:.: :..:||.|..|||||:..||      :
  Fly   625 NNNLCLWWVSEEEL-DKDKTYDAFISYSHKDEELISK-LLPKLESGPHPFRLCLHDRDWLVGDCI 687

  Fly  1084 PPQASHLQLVEGARASRKIILVLTRNLLATEWNRIEFRNAFHESLRGLAQKLVII------EETS 1142
            |.     |:|.....|:::|:||:::.:.:.|.|:|||.|:..:|:...::::||      ....
  Fly   688 PE-----QIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNG 747

  Fly  1143 VSAEAEDVAELSPYLKSVPSNRLLTCDRYFWEKLRYAIP 1181
            :.:|.....:|:.|||        ..|..||.||.||:|
  Fly   748 IDSELRAYLKLNTYLK--------WGDPLFWSKLYYAMP 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
18w	NP_476814.1	leucine-rich repeat	66..91	CDD:275380
		leucine-rich repeat	92..115	CDD:275380
		LRR_8	115..181	CDD:404697
		leucine-rich repeat	116..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..201	CDD:275380
		LRR	210..592	CDD:443914	61/265 (23%)
		leucine-rich repeat	212..236	CDD:275380
		leucine-rich repeat	237..260	CDD:275380
		leucine-rich repeat	261..284	CDD:275380
		leucine-rich repeat	285..308	CDD:275380
		leucine-rich repeat	309..334	CDD:275380
		leucine-rich repeat	335..358	CDD:275380	4/15 (27%)
		leucine-rich repeat	359..382	CDD:275380	5/25 (20%)
		leucine-rich repeat	383..406	CDD:275380	2/22 (9%)
		leucine-rich repeat	407..430	CDD:275380	5/22 (23%)
		leucine-rich repeat	431..451	CDD:275380	7/19 (37%)
		leucine-rich repeat	454..477	CDD:275380	9/22 (41%)
		leucine-rich repeat	478..499	CDD:275380	5/25 (20%)
		leucine-rich repeat	502..525	CDD:275380	6/22 (27%)
		leucine-rich repeat	526..548	CDD:275380	6/23 (26%)
		leucine-rich repeat	590..617	CDD:275380	8/28 (29%)
		leucine-rich repeat	618..641	CDD:275380	5/22 (23%)
		leucine-rich repeat	642..689	CDD:275380	5/46 (11%)
		LRRCT	679..736	CDD:214507	0/56 (0%)
		LRR	<775..>920	CDD:443914	39/151 (26%)
		leucine-rich repeat	775..796	CDD:275380	8/22 (36%)
		leucine-rich repeat	797..817	CDD:275380	6/23 (26%)
		leucine-rich repeat	818..841	CDD:275380	8/23 (35%)
		leucine-rich repeat	842..865	CDD:275380	7/22 (32%)
		leucine-rich repeat	866..889	CDD:275380	5/22 (23%)
		leucine-rich repeat	890..911	CDD:275380	0/20 (0%)
		TIR	1045..1183	CDD:214587	47/149 (32%)
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	110/507 (22%)
		leucine-rich repeat	185..207	CDD:275380	7/22 (32%)
		leucine-rich repeat	209..232	CDD:275380	9/22 (41%)
		leucine-rich repeat	233..261	CDD:275380	5/27 (19%)
		leucine-rich repeat	262..284	CDD:275380	6/22 (27%)
		leucine-rich repeat	285..309	CDD:275380	6/23 (26%)
		leucine-rich repeat	310..333	CDD:275380	8/36 (22%)
		leucine-rich repeat	334..357	CDD:275380	8/22 (36%)
		leucine-rich repeat	358..381	CDD:275380	5/37 (14%)
		leucine-rich repeat	445..482	CDD:275380	11/39 (28%)
		leucine-rich repeat	483..505	CDD:275380	8/23 (35%)
		TIR	643..779	CDD:214587	47/150 (31%)