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Protein Alignment 18w and egg-6

DIOPT Version :9

Sequence 1:	NP_476814.1	Gene:	18w / 37277	FlyBaseID:	FBgn0004364	Length:	1385	Species:	Drosophila melanogaster
Sequence 2:	NP_492348.1	Gene:	egg-6 / 172670	WormBaseID:	WBGene00010621	Length:	961	Species:	Caenorhabditis elegans

Alignment Length:	465	Identity:	113/465 - (24%)
Similarity:	217/465 - (46%)	Gaps:	48/465 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 KELSELHLGDNNIRQLPEGVWCS-MPSLQLLNLTQNRIRSAEFLGFSEKLCAGSALSNANGAVSG 208
            |.:..|.....:::.:.:.|..| :..|.:||.|..:|.|..|.|
Worm    36 KSMIILSCNGEDVKTIAQTVGTSQIDELHILNGTDVKIESLPFNG-------------------- 80

  Fly   209 GSELQTLDVSFNELRSL-PDAWGASRLRRLQT----LSLQHNNISTLAPNALAGLSSLRVLNISY 268
               |:|:.:..:.|:|. |.||     |.::.    :::..|.:.|:.  ....||:|..:|::.
Worm    81 ---LRTIAILNSTLQSFSPTAW-----RHVEATIEHITINGNELKTVP--VFGNLSTLMSMNLNS 135

  Fly   269 NHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLE-QLLVLDLSGNQLTSHHVDNSTFAGL 332
            |.:.|:|.:||.|...|.:|.|:.|.:.:.|...|..:: .|::||:|||.|.:  :........
Worm   136 NQISSIPDKAFNGLSALTQLRLENNAICDFPPKSLDAVKASLVLLDVSGNCLDA--IPAQILRNA 198

  Fly   333 IRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLD 397
            ..|:.|:|.:|.::.|.:.....|.||:.|.::||::..|...||:.:..|..|.|.:|.:.|||
Worm   199 ANLMYLDLGSNNISEINNFELMNLPFLRELRVQNNTLRRIHPMAFMNVPQLQYLYLQDNIISTLD 263

  Fly   398 NRIFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTEVPE-AVQDLSMLKTLDLGE 461
            .....|...|..|.::||.:..:.|  .::..:||::.:..|.:|::.. |..:...|:.:.:..
Worm   264 GNRLQGFKNLEVLDVSNNALYALPS--LKDLPNLKQVRVDGNLITKIETLAFSNNPNLQLISVQN 326

  Fly   462 NQISEFKNNTFRNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEI 526
            |.|.:...|:|.:|::|..|.:.:|.:..|..|||..:..|..|::..|.:.:::..:|.:...:
Worm   327 NNIVQISRNSFESLDKLVVLLVGNNSLAKIERGMFDGMKNLQQLSIRNNTLTALDASSFAQLAHL 391

  Fly   527 EAIRLDKNFLTDI-NGIFATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYI---EALGNY 587
            ..:.|..|.:.|| .|.|..|:.|.||:||.|.:..|..:.....:..:.:.||.:   |:...:
Worm   392 TTLDLGHNKIHDIEEGTFDKLSKLFWLDLSNNKISGFKTSVFKKKISNILLDGNQLICDESFNEF 456

  Fly   588 --YKLQEEIR 595
              |.:..::|
Worm   457 LTYLIANKVR 466

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.