DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16898 and CHKov1

DIOPT Version :9

Sequence 1:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001097918.1	Gene:	CHKov1 / 43067	FlyBaseID:	FBgn0045761	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	419	Identity:	110/419 - (26%)
Similarity:	201/419 - (47%)	Gaps:	31/419 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPNWLTEEYLQPKLRAYYKDDQLKVVKVWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYII 66
            :|:|:|.|..:..|::.. |...||....|:..:..|.||.:.|.|:::|::..||..:..:|::
  Fly     6 IPDWVTAERFEDVLKSNV-DGYSKVRNFKAEMGSAAGDNYATNMLRVNIEVELQDGTTKELSYMV 69

  Fly    67 KESLSEDCPQAKVFLEYDVYNREMDMYEFILPKMNELLQEVGLTGKFTADTIFV---DREYRTII 128
            |.....:. ..::....:::..|..||..::|:|..|.:..|:...|.|.:..:   ..||  |.
  Fly    70 KLPRQREI-NKEMMKHNNIFEIERTMYNLVVPEMEALYKAAGVEVTFGAKSYELKNAQTEY--IS 131

  Fly   129 LEDLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAAS---IVVKQRHPELLTKSLFIHCFSRDNK 190
            ||||....:.||:|::.||.|||:..|..||::|||:   :..|.::||::....    |..:|:
  Fly   132 LEDLCIKGFKNANRLEGLDQAHTERVLRKLAQWHAATAVRVATKGQYPEIVLNGF----FKEENR 192

  Fly   191 G-YTEVYEGVLSAFIRFI-----NEQPVLKKKYGNKLQKIHENIMDYGARTFEVGEQELLTLSHG 249
            . ..::..|:...|::..     ||      .|..|::.:.:.::|...:...|...|...|:||
  Fly   193 PMMNDMMNGMGQVFVKCCSTYEGNE------AYIEKVKALKDVMIDELFKMCVVDPTEFNVLNHG 251

  Fly   250 DCWTTNFLYQYDDASNPQSAVAIDFQFSNFTSPVNDLHQFF--TVSLRDEVQDMESVLVEKYYSD 312
            |.|:.|.::|||::...:....:|||.|.:.:...||:.|.  :..|.|::...: ..|:.|:.:
  Fly   252 DSWSNNIMFQYDESGKIKEVYMVDFQVSKYGTVAQDLYYFLISSTKLEDKLSKFD-YYVKVYHDN 315

  Fly   313 LKTNVDTLSYKGIFPSLQGFQKQ-FESRRFMCLLAHLFKPVIIYDGTEVSSDFSSVYKDTEEGIR 376
            |..::..|.|....|||:...|. ::...|...:|......::.|.|| |:.|.:...|:.||..
  Fly   316 LVEHLKILKYSKPLPSLRDIHKSLYKYGTFAYSVATGVMAAVLVDPTE-SASFENFVGDSAEGAD 379

  Fly   377 FQKAIYANERVLKSATKLLAMLDAKGVLN 405
            ||..:|.|.|..|....:|..|..:|.|:
  Fly   380 FQMKMYNNPRYRKHMQAILPWLLNRGALD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	76/298 (26%)
CHKov1	NP_001097918.1	EcKinase	41..325	CDD:397213	76/297 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12414
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.810