DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16898 and CG11891

DIOPT Version :9

Sequence 1:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	156/409 - (38%)
Similarity:	246/409 - (60%)	Gaps:	6/409 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLPNWLTEEYLQPKLRAYYKDDQLKVVKVWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYI 65
            ::|.|||.:|::.|||:|:::|.|::|.:..|.|...|:||.|::|||:||........:..|..
  Fly    11 VVPAWLTRDYVEQKLRSYFRNDSLRLVNLDIKLALGNGENYSSVITRIYVEYTTDKSKDKQSTRF 75

  Fly    66 IKESLSEDCPQAKVFLEYDVYNREMDMYEFILPKMNELLQ-EVGLTGKFTADTIFVDREYRTIIL 129
            .:  .::..|.|:|.|.|.|||||:|:||.|||:|.|::: |:..:.|..|.|::|||:..:||.
  Fly    76 TR--FADAGPAAQVLLSYGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTVYVDRKRDSIIF 138

  Fly   130 EDLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAASIVVKQRHPELLTKSLFIHCFSRDNKGYTE 194
            ||::..||..|||:|:|||.||.|.||.||.||||...:.:|.|.:..|:.....|::..:||..
  Fly   139 EDMSLENYRVADRLKKLDLEHTHLVLEKLANFHAAGAALAERQPGIFAKNFDRGFFNQHTRGYEP 203

  Fly   195 VYEGVLSAFIRFINEQPVLKKKYGNKLQKIHENIMDYGARTFEVGEQELLTLSHGDCWTTNFLYQ 259
            :.:.:|.|..|.:..:|.|.::|..|:.::.||:|:||.|:..:...:.|||:|||.||||.::|
  Fly   204 IMKNLLMALSRSLELEPDLCQRYQAKIDRLVENVMEYGERSTTIVPGDFLTLAHGDLWTTNIMFQ 268

  Fly   260 YDDASNPQSAVAIDFQFSNFTSPVNDLHQFFTVSLRDEVQ-DMESVLVEKYYSDLKTNVDTLSYK 323
            |||..:|.:|:.||||||.:.||..|||.||:.:|:.::: ..:..||:.||..|...:..:.|.
  Fly   269 YDDKGHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQPELVQFYYYKLNAALKKVQYS 333

  Fly   324 GIFPSLQGFQKQFESRRFMCLLAHL-FKPVIIYDGTEVSSDFSSVYKDTEEGIRFQKAIYANERV 387
            |..|||..|.:||.:|.|....|.| |:|.:.|.|.|.:| ...:...:|:|:||:...:..|..
  Fly   334 GNVPSLFVFHQQFRNRSFYAAFASLIFEPTMTYTGKEEAS-MDQIISLSEKGMRFKDDAFQAEET 397

  Fly   388 LKSATKLLAMLDAKGVLNL 406
            .|.....|..||..|:|::
  Fly   398 RKKMRLTLPFLDHLGLLDV 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	113/286 (40%)
CG11891	NP_001027211.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H115919
Inparanoid	1	1.050	53	1.000	Inparanoid score	I4082
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	7	7.060