DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16898 and CG13360

DIOPT Version :9

Sequence 1:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	114/429 - (26%)
Similarity:	195/429 - (45%)	Gaps:	48/429 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PNWLTEEYLQPKLRAYYKDDQLKVVK-VWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYII 66
            |.:|.|::.:..|....:|.::.:.| ::::.:...|:||.|.:.|.....:.....|.....:|
  Fly    15 PKYLNEDFFKAALEDGLRDMRVDIKKIIFSESSGGGGENYCSKIYRAKALYRSSKRQLDEELALI 79

  Fly    67 KESLSEDCPQAKVFLEYDVYNREMDMYEFILPKMNELLQEVGLTGKFTADTIFVDRE-YRTIILE 130
            .:|:: ..|..:...|..||.||...|..:|.|:..|   :|...||.|..::..|| .:||:.:
  Fly    80 VKSIA-ITPATQFLEELAVYLREKIFYFDVLGKLEVL---IGDGSKFGAKCLYTTREPIQTIVFD 140

  Fly   131 DLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAASIVVKQRHP---ELLTKSLFIHCFSRDNKGY 192
            ||.||.|..|.|...|:..|..:.|:.|.||||:|:|:.::.|   |..|..:....:.|.|:
  Fly   141 DLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEKEPSVREHFTTGMLDENYIRTNE-- 203

  Fly   193 TEVYEGVLSAFIRFINEQ-----PVLKKKYGNKL--QKIH---ENIMDYGARTFEVGEQELLTLS 247
                     .||.|:..|     .|:.|..|.:|  :|:|   :||.:....|......|:..|:
  Fly   204 ---------RFINFMTLQCRTLANVVSKWPGYELLAEKLHRHCDNIKENLVTTGRPLPGEITVLN 259

  Fly   248 HGDCWTTNFLYQYDD--ASNPQSAVAIDFQFSNFTSPVNDLHQFFTVSLR-DEVQDMESVLVEKY 309
            |||.|..||:|:|||  .:.|..|:.:|||.|.|.||..|::.|...|:: |.:......|::.|
  Fly   260 HGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFFLNSSVQLDVLIHRREFLIQTY 324

  Fly   310 YSDLKTNVDTLSYKGIFPSLQGFQKQFESRR-FMCLLAHLFKPVII------YD-GTEVSSDFSS 366
            |:.|:.:::.: :....||....|::..:|. :....::.|.|::.      || ..|..||...
  Fly   325 YASLRDSLERM-HSAFVPSYADIQQEIRARELYGFFSSYAFLPMVTMKKEDSYDISIEALSDQDF 388

  Fly   367 VYKDTEEGIRFQKAIYANERVLKSATKLLAMLDAKGVLN 405
            ..|      :.|....:|.|...:....|...|..|:.:
  Fly   389 AKK------KVQLMFSSNPRTTDTLRYALRRFDDLGIFD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	90/301 (30%)
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	90/299 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459168
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860