Protein Alignment CG8654 and SV2B

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 119/602 - (19%)
• Similarity: 197/602 - (32%)
• Gaps: 222/602 - (36%)

  Fly    78 DECSETEFDTSVF-----------QSTIITEWNLTCESKQLASLSQS-------IVMLGILFGSI 124
            |||....|...:|           ....:..:.|....|.:. ||.|       ||.||::.|:.
Human   100 DECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMC-LSSSKKGMLGMIVYLGMMAGAF 163

  Fly   125 LFGMFADRYGRRPAFLTCCFMQL-ITGLIVCVSPY---YWFYCLFRFLVAVATAGTMTTSFVLLM 185
            :.|..||:.||:...    .|.| :......:|.:   |..:...|.:..:...|.:...|....
Human   164 ILGGLADKLGRKRVL----SMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFS 224

  Fly   186 EIVGPKKRE----------MVAILYQ-------IP-----FNIGHASLALFAYFIREWRWFQFSI 228
            |.:..:||.          |...||.       ||     |::|      ..|....||.|....
Human   225 EFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMG------TNYHFHSWRVFVIVC 283

  Fly   229 TIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN----------------KAP---TE 274
            .:...|.::.:..:|||||:|...||.|::..||:::...|                |.|   .|
Human   284 ALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDE 348

  Fly   275 TIRPEIEAAYGALAARQPVKKGTVVDLFRT-----------PYMRIKTIFMANNWLVVCMVYYGT 328
            .|  ||:::.|....|..|:..|:   |:.           || |:.|:.:|..|..:...|||.
Human   349 FI--EIQSSTGTWYQRWLVRFKTI---FKQVWDNALYCVMGPY-RMNTLILAVVWFAMAFSYYGL 407

  Fly   329 A-------------QYVSAL---------GGNI-------------------------------- 339
            .             :|.|.:         |..|
Human   408 TVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDT 472

  Fly   340 -----------------------------------------FISNA------------------- 344
                                                     ||::.
Human   473 FFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFL 537

  Fly   345 --IAAGVG----IPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGL 403
              :.:.:|    :||..:.||:...:||.|.:..|...||:....|...::::..:...|    |
Human   538 IYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQC----L 598

  Fly   404 F-GASITFPNVY-LYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAY-GLW-VAPLIFGI 464
            | |.||...|.. :...||:||..|::..|:.:.:.:.|:|:...|  .|:: |:. |.|::...
Human   599 FCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTI--FASFVGITKVVPILLAA 661

  Fly   465 FSIL-AMLGTIFLPETR 480
            .|:: ..|..:.|||||
Human   662 ASLVGGGLIALRLPETR 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	116/595 (19%)
		MFS	87..477	CDD:119392	110/588 (19%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	119/602 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940