DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8654 and OCT4

DIOPT Version :9

Sequence 1:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	141/483 - (29%)
Similarity:	234/483 - (48%)	Gaps:	41/483 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCKTENVTDPCSDECSETEFDTSVFQ-- 91
            |:|.|:||..|.:..:......:||:..||........|    |...|.......|.|.|.::
plant    43 GEFGRWQLKHFVLTCIAWALEAFHTMVMIFADQEPEWRC----VGSDCRVGSLNCELDPSSWEWT 103

  Fly    92 ----STIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFAD-RYGRRPAFLTCCFMQLITGL 151
                |:.::||.|.|..|....|.|::...|.:.|:.:||..:| :.||:.:....|.:..|.|:
plant   104 AGKGSSTVSEWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGI 168

  Fly   152 IVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAY 216
            ....||.||.|.:.|||...:|.|...|:|||..|.:||.||.:..:.....|:.|.|.|:..||
plant   169 ATAFSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVAGMSTFYFFSAGIAVLSGIAY 233

  Fly   217 FIREWRWFQFSITIFSIVF-VIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN-----KAPTET 275
            ..|.||......::.|::| :|.|..:.|||||....||:|:::|::..|||.|     ...|..
plant   234 VFRSWRELFIVSSLPSLLFLLIVIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAGVTLA 298

  Fly   276 IRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIF 340
            :..::|...|   .|....:|::.|:..:|.||::.:........|.:||||.:..|..|..|::
plant   299 LDDDVENNNG---ERNTAVEGSLKDVILSPLMRMRLVISVAISFTVSIVYYGLSLNVGNLKTNLY 360

  Fly   341 ISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACL-------STQAEAVRVTC 398
            ::..:.|...:|...:.|::....|||.   ||.|......:.  ||       :...::||:..
plant   361 LNVFVNAVSEMPAFAITAVLLDKYGRKP---LSIGTQWFSCVF--CLVGFSVWGAGPWKSVRMVS 420

  Fly   399 ATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFG 463
            ..:|:||.:.|:..:::|..||||||||::.:|..:...::|:|:||.:|.|.      ..|.||
plant   421 GVLGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPFVVVLG------EELPFG 479

  Fly   464 IFSILAMLG---TIFLPETRGTPLPETL 488
            :|::..::|   ..:||||...||.:|:
plant   480 VFAVCGLVGGGLAFYLPETLNKPLYDTM 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	126/424 (30%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	119/412 (29%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	121/419 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	225	1.000	Domainoid score	I682
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464838at2759
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm8406
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	10.030