Protein Alignment CG8654 and Slc22a16

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 549
• Identity: 141/549 - (25%)
• Similarity: 242/549 - (44%)
• Gaps: 81/549 - (14%)

  Fly    24 IISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAAPTPLSCK-----------------TEN 71
            |...||.|.|:|:..:.|........|.|.|..:||:.....:||                 .|:
Mouse     9 IFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLED 73

  Fly    72 VTDPCSDE-------------------CSET-------------------------EFDTSVFQS 92
            :....|.|                   ||.|                         .:|.|.:::
Mouse    74 ILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRN 138

  Fly    93 TIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTC----CFMQLITGLIV 153
            :.:..:||.|:.|..|.:.|.:::.|::.|||.|...:||:|||.| |.|    .|...|..|.:
Mouse   139 SAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMA-LWCTSIGVFFFGIASLFI 202

  Fly   154 CVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFI 218
            .   .|..:.:.||.:.:|::|.....||.:|||:|.|.|...:|.....|.||...:||.:|.:
Mouse   203 F---DYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLL 264

  Fly   219 REWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPT----ETIRPE 279
            :.|..:|..:.|.:..|::..|::||:|.||.:.|:..::...::.:|..||:.:    |.:..:
Mouse   265 KTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLD 329

  Fly   280 IEAAYGALAARQP--VKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFIS 342
            :..::.    :.|  ::|..:.|||....:...|:.:..:|....:.||...:.|.....|..:.
Mouse   330 VTRSHN----KSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLY 390

  Fly   343 NAIAAGVGIPG-TCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGA 406
            ..:...:.||. .||| :..|.:||:||:||....|:|..:|...:.:..:..:...|.:.....
Mouse   391 LLLVGAMEIPAYICLC-IWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVI 454

  Fly   407 SITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAML 471
            |..|..:|||..||:||.||...||..:||..:.||..|.....:...:::..::|||.:||:.|
Mouse   455 SSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGL 519

  Fly   472 GTIFLPETRGTPLPETLEDGETFGRKKKD 500
            .::.||||:.||:..|.|..|....:.||
Mouse   520 LSLKLPETQDTPMKSTWETTEQQVPENKD 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	116/412 (28%)
		MFS	87..477	CDD:119392	109/400 (27%)
Slc22a16	NP_081848.1	2A0119	14..535	CDD:273328	134/529 (25%)
		MFS	163..525	CDD:119392	102/370 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950