Protein Alignment CG8654 and Slc22a4

DIOPT Version :10

• Sequence 1: NP_611451.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 143/540 - (26%)
• Similarity: 246/540 - (45%)
• Gaps: 73/540 - (13%)

  Fly    22 DPIISQIGDFRRYQLFFFFIVLLCKFGTGWHTLGHIFLAA------------------------- 61
            |.:|:.:||:..:|...||::.......|::.:..:|||.
  Rat     5 DEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSAWRNHSIPL 69

  Fly    62 ------PTPLSCKTENVT----------DPCSD---------ECSE-TEFDTSVFQSTIITEWNL 100
                  ..|.||:...:.          :|..|         .|.: .|:...||.|||:|||||
  Rat    70 ETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEWNL 134

  Fly   101 TCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLF 165
            .||......|:.|:..:|:|.||.:.|..:||:||:........:|.....:...|..:..:.:.
  Rat   135 VCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVL 199

  Fly   166 RFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIP-FNIGHASLALFAYFIREWRWFQFSIT 229
            ..:|.:........:|:|..||:....|.:.:.|.... |.||:..|.|||||||:||....::|
  Rat   200 FAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALT 264

  Fly   230 IFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN--KAPTETIRP-EIEAAYGALAARQ 291
            :..:..|...|.:|||||||.:..:.:::.:|::|.||.|  .||.....| |::...   :.:|
  Rat   265 LPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQELN---SLKQ 326

  Fly   292 PVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCL 356
              :|..::|||:|..:...|:.....|::..:.|:..:..|..|.|:::::..::..:.:|....
  Rat   327 --QKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFT 389

  Fly   357 CALMTKYLGRK----KTLLLSNGCSALGLILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYG 417
            ..|:.:.|.|:    ..|....|.    |:|:..:......|.:....:|.||.:..|..:|::.
  Rat   390 AWLLLRTLPRRYIIAGVLFWGGGV----LLLVQVVPEDYNFVSIGLVMLGKFGVTSAFSMLYVFT 450

  Fly   418 GELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGT 482
            .||:||:||:..||:.||..|:|||:||..|.|.||...:..::.|..::|..:.|:|.||:.|.
  Rat   451 AELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGV 515

  Fly   483 PLPETLED-----GETFGRK 497
            .|||.||.     |...|:|
  Rat   516 TLPENLEQMQKVRGFRCGKK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_611451.1	MFS_SLC22	82..477	CDD:340875	115/403 (29%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	134/515 (26%)