Protein Alignment CG8654 and SLC22A23

DIOPT Version :9

• Sequence 1: NP_001246441.1
• Gene: CG8654 / 37275
• FlyBaseID: FBgn0034479
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 114/479 - (23%)
• Similarity: 207/479 - (43%)
• Gaps: 65/479 - (13%)

  Fly    70 ENVTDPCSDECSETE-----FDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMF 129
            :||...|   |.:.|     :||...:......|:|.|::.....:::..:::|::||.::.|..
Human   213 QNVVSKC---CQQQETGALPWDTDTKRWRPELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCI 274

  Fly   130 ADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKRE 194
            ||..||||..|......||.||.|.:|.....:...||......||.:.|.:.|.:|:..|.||.
Human   275 ADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRF 339

  Fly   195 MVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSI 259
            |:.::.......|...:...|...|:|:..|..|....::.::|..:.|||.|||..|.:.:.:.
Human   340 MITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAK 404

  Fly   260 KILEKIAKCNKAPTE----TIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNW-- 318
            :::....:.|:...|    .:.||:|..    .:|:| ||..:|          |.:...|.|
Human   405 RLILHFTQKNRMNPEGDIKGVIPELEKE----LSRRP-KKVCIV----------KVVGTRNLWKN 454

  Fly   319 -LVVC---MVYYGTAQ-YVSALGG---------NIFISNAIAAGVGIPGTCLCALMTKYLGRKKT 369
             :|:|   :..||... :..::.|         |.:......|.:.:.......::.::|||:..
Human   455 IVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGG 519

  Fly   370 LLLSNGCSALGLILLACL------------STQAEAVR----VTCATIGLFGASITFPNVYLYGG 418
            |||....:||..:|...|            |..:::|:    :..:.:|:|.:.........:..
Human   520 LLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCA 584

  Fly   419 ELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETRGTP 483
            |:.|||:|..|:||.......|.:.||:|......|.::..:||...:::.::..:.|||:|...
Human   585 EITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQN 649

  Fly   484 LPETLEDGETFGR------KKKDQ 501
            |||.:.:||.:.|      ||.:|
Human   650 LPENISNGEHYTRQPLLPHKKGEQ 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8654	NP_001246441.1	SP	85..487	CDD:273317	102/437 (23%)
		MFS	87..477	CDD:119392	95/425 (22%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	99/423 (23%)
		MFS	259..>388	CDD:119392	35/128 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010